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The effect of deferoxamine on tolerance to secondary ischaemia caused by venous obstruction

The effect of deferoxamine on tolerance to secondary ischaemia caused by venous obstruction,10.1016/0007-1226(89)90007-6,British Journal of Plastic Su

The effect of deferoxamine on tolerance to secondary ischaemia caused by venous obstruction   (Citations: 12)
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Journal: British Journal of Plastic Surgery - BRIT J PLAST SURG , vol. 42, no. 4, pp. 422-424, 1989
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    • ...Ischemia, a condition where the blood flow is inadequate to support the needs of the tissue, continues to be a significant problem for reconstructive surgeons [2, 4]. Im et al. found that administering allopurinol prior to resumption of flow significantly lessened tissue necrosis in an experimental study with a rodent abdominal flap model [20]...

    M. Deveciet al. Alpha-tocopherol and ginkgo biloba treatment protects lipid peroxidati...

    • ...Correspondence to: B. ~elik6z, GATA Plastik ve Rekonstrtiktif Cerrahi A. Dali, TR-06018 Etlik, Ankara, Turkey greatest problem for surgeons and it presents a significant challenge, thus various agents have been used to minimize the risk of tissue injury during ischemic period and to increase flap survival [1, 3, 16]...
    • ...Deferoxamine is also a potent iron chelating agent and free radical scavenger, characteristics of which could be of benefit for ischemic tissue [1, 2, 13, 16, 24, 42]...
    • ...Deferoxamine - protect lipids by scavenging peroxyl radicals without reacting in further chain propagating steps [1, 2, 16, 29, 40]...

    B. Çeliközet al. The effects of gingko biloba extract and deferoxamine on flap viabilit...

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