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Knocking Down Cav1 Calcium Channels Implicated in Th2 Cell Activation Prevents Experimental Asthma

Knocking Down Cav1 Calcium Channels Implicated in Th2 Cell Activation Prevents Experimental Asthma,10.1164/rccm.200907-1166OC,American Journal of Resp

Knocking Down Cav1 Calcium Channels Implicated in Th2 Cell Activation Prevents Experimental Asthma   (Citations: 4)
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M. D. Cabral, P.-E. Paulet, V. Robert, B. Gomes, M.-L. Renoud, M. Savignac, C. Leclerc, M. Moreau, D. Lair, M. Langelot, A. Magnan, H. Ysselhttp://academic.research.microsoft.com/io.ashx?type=5&id=33771178&selfId1=0&selfId2=0&maxNumber=12&query=
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    • ...CD40 on DCs Mouse Intraperitoneal siRNA, transfection in vitro OVA allergic rhinitis model [10] Cav1 on Th2 cells Mouse Intranasal antisense OVA asthma model [40]...
    • ...Inhibition of these channels by antisense oligonucleotides was effective in active experimental asthma, preventing airway inflammation, Th2 cell activation, and AHR without affecting Th1 responses [40]...

    Tania Maeset al. Gene Therapy for Allergic Airway Diseases

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