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Tinnitus and inferior colliculus activity in chinchillas related to three distinct patterns of cochlear trauma

Tinnitus and inferior colliculus activity in chinchillas related to three distinct patterns of cochlear trauma,10.1002/jnr.21699,Journal of Neuroscien

Tinnitus and inferior colliculus activity in chinchillas related to three distinct patterns of cochlear trauma   (Citations: 22)
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Journal: Journal of Neuroscience Research - J NEUROSCI RES , vol. 86, no. 11, pp. 2564-2578, 2008
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    • ... Mounting evidence suggests that tinnitus can be linked with increased spontaneous neuronal activity ...

    Avril Genene Holtet al. Evidence of Key Tinnitus-Related Brain Regions Documented by a Unique ...

    • ...Noise (especially impulse noise), stress, ototoxic substances, sudden hearing loss as well as head and neck injuries are factors that may contribute to the pathogenesis of tinnitus [7-9]...

    Birgit Mazureket al. Evaluation of vardenafil for the treatment of subjective tinnitus: a c...

    • ...12). We are, however, far from fully understanding the nature of the abnormalities that cause many forms of tinnitus, and how it is brought about is still being investigated; hypotheses regarding the pathology of tinnitus are constantly created and abandoned [7]...
    • ...Ephaptic transmission between axons in the auditory nerve has been suggested [7, 8], but some forms of ephaptic transmission between nerve cells in the central nervous system may also be involved...

    Aage R. Møller. Pathology of the Auditory System that Can Cause Tinnitus

    • ...Chronic increases in bursting activity have been observed in the auditory nerve following noise exposure [6], in the DCN following noise exposure [14], and in the IC following salicylate and noise exposure [23, 41]...
    • ...No increased bursting has been found in the auditory cortex following noise exposure, salicylate, or quinine [23, 46, 68, 69]...
    • ...In addition to increased discharge rates and increased bursting activity, there is evidence for an increase in synchrony of discharges among neurons in the IC following noise exposure [23] and in the auditory cortex following noise or quinine administration [27, 30, 69]...
    • ...Tinnitus percepts in animals and tinnitus-related changes in activity in the IC have been found to be associated with loss of spiral ganglion cells [23]...

    James A. Kaltenbach. The Neuroscientist

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