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Specificity of molecular interactions in transient protein-protein interaction interfaces

Specificity of molecular interactions in transient protein-protein interaction interfaces,10.1002/prot.21056,Proteins-structure Function and Bioinform

Specificity of molecular interactions in transient protein-protein interaction interfaces   (Citations: 10)
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Journal: Proteins-structure Function and Bioinformatics - PROTEINS , vol. 65, no. 3, pp. 593-606, 2006
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    • ...According to previous research, the extending conformation would be preferred for an aromatic residue in open surrounding [28,29]...
    • ...Firstly, Tyr and Trp have been found to be able to form more close interactions to antigen proteins than other peers because of the aromatic and hydroxyl groups in their side chain [21,28]...

    Di Wuet al. Stacking and energetic contribution of aromatic islands at the binding...

    • ...[1-2]. These distinct biological effects reflect corresponding protein functions in living organisms...

    Ying-Tsang Loet al. Using Solid Angles to Detect Protein Docking Regions by CUDA Parallel ...

    • ...Studies of these interfaces have produced variable results, partly because they have examined different types of proteins; hence, when comparing findings for different proteins, it is important to consider the types of proteins (16,17)...
    • ...Eighteen molecular interaction types, which we have defined previously (17), are analyzed on the basis of their occurrences in each interface residue...
    • ...Eighteen molecular interactions are considered, composed of canonical hydrogen bonds, noncanonical hydrogen bonds, electrostatic interactions and p–ring system-related interactions, all of which are known to be energetically important interactions (17)...

    Kyu-il Choet al. A feature-based approach to modeling protein-protein interaction hot s...

    • ...Thanks to a large number of recent X-ray and NMR structures of protein∶protein, protein∶DNA, and protein∶RNA complexes, a lot of valuable information about the general features of such complexes has been discovered ...

    Andrija Tomovicet al. Computational Structural Analysis: Multiple Proteins Bound to DNA

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