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Downregulation of pro-inflammatory cytokines by lupeol measured using cytometric bead array immunoassay

Downregulation of pro-inflammatory cytokines by lupeol measured using cytometric bead array immunoassay,10.1002/ptr.2844,Phytotherapy Research,Sheikh

Downregulation of pro-inflammatory cytokines by lupeol measured using cytometric bead array immunoassay   (Citations: 4)
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Journal: Phytotherapy Research - PHYTOTHER RES , vol. 24, no. 1, pp. 9-13, 2010
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    • ...The oral administration of lupeol (25 to 200 mg/kg) was also reported to produce a dose-related inhibition of IL-2, IFN-g and TNF-a, in mice pleural exudates [46]...

    Daniel L Lucettiet al. Anti-inflammatory effects and possible mechanism of action of lupeol a...

    • ...As demonstrated by Ahmad [26], lupeol causes a dose-dependent inhibition of both total leukocyte count and exudate volume in carrageenan-induced pleurisy in mice, and exerts a dose dependent inhibitory effect on IL-2, IFN-c and TNF-a present in pleural fluid...
    • ...These observations suggest that lupeol may act by neutralization of the pro-inflammatory cytokines that can efficiently control inflammation, revealing the possibility of modulating the cytokine balance as a therapeutic strategy that results in systemic inhibition of the inflammatory state [26]...

    Weuller F. de Moraeset al. Triterpenes involved in the anti-inflammatory effect of ethanolic extr...

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