Kinetics of exocytosis in adrenal chromaffin cells

Kinetics of exocytosis in adrenal chromaffin cells,10.1006/scdb.1996.0132,Seminars in Cell & Developmental Biology,Kevin D. Gillis,Robert H. Chow

Kinetics of exocytosis in adrenal chromaffin cells   (Citations: 10)
BibTex | RIS | RefWorks Download
Upon repetitive or maintained stimulation, chromaffin cells secrete catecholamines initially at a very high rate which then relaxes with multiple kinetic components. The complex kinetics are often modeled as resulting from the successive depletion of several functional pools of secretory granules which may reflect specific protein-mediated steps in granule maturation. The fastest component represents granules fully primed for exocytosis. This ‘readily releasable pool’ may, under some circumstances, consist of only about a dozen granules which can be released within tens of milliseconds. Modulating the size of this pool may be an important way for cells to regulate secretion.
Journal: Seminars in Cell & Developmental Biology - SEMIN CELL DEV BIOL , vol. 8, no. 2, pp. 133-140, 1997
Cumulative Annual
View Publication
The following links allow you to view full publications. These links are maintained by other sources not affiliated with Microsoft Academic Search.
Sort by: