Academic
Publications
Individual Variability in Brain Activity: A Nuisance or an Opportunity?

Individual Variability in Brain Activity: A Nuisance or an Opportunity?,10.1007/s11682-008-9049-9,Brain Imaging and Behavior,John Darrell Van Horn,Sco

Individual Variability in Brain Activity: A Nuisance or an Opportunity?   (Citations: 3)
BibTex | RIS | RefWorks Download
Functional imaging research has been heavily influenced by results based on population-level inference. However, group average results may belie the unique patterns of activity present in the individual that ordinarily are considered random noise. Recent advances in the evolution of MRI hardware have led to significant improvements in the stability and reproducibility of blood oxygen level dependent (BOLD) measurements. These enhancements provide a unique opportunity for closer examination of individual patterns of brain activity. Three objectives can be accomplished by considering brain scans at the individual level; (1) Mapping functional anatomy at a fine grained analysis; (2) Determining if an individual scan is normative with respect to a reference population; and (3) Understanding the sources of intersubject variability in brain activity. In this review, we detail these objectives, briefly discuss their histories and present recent trends in the analyses of individual variability. Finally, we emphasize the unique opportunities and challenges for understanding individual differences through international collaboration among Pacific Rim investigators.
Journal: Brain Imaging and Behavior - BRAIN IMAGING BEHAV , vol. 2, no. 4, pp. 327-334, 2008
Cumulative Annual
View Publication
The following links allow you to view full publications. These links are maintained by other sources not affiliated with Microsoft Academic Search.
    • ...Miller et al. (2002; Van Horn et al. 2008) specifically discussed the issue of inter-individual variability in fMRI studies, including variability associated with different cognitive strategies (i.e., fMRI research has been heavily influenced by results based on populationlevel inference) and emphasized the unique opportunity and importance of understanding individual differences...

    C. J. AineLet al. Development and Decline of Memory Functions in Normal, Pathological an...

Sort by: