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The acute dose-related effects of ethanol on right ventricular function in anesthetized dogs

The acute dose-related effects of ethanol on right ventricular function in anesthetized dogs,10.1016/0741-8329(92)90026-7,Alcohol,R KETTUNEN,J TIMISJA

The acute dose-related effects of ethanol on right ventricular function in anesthetized dogs   (Citations: 5)
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Journal: Alcohol , vol. 9, no. 2, pp. 149-153, 1992
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    • ...In a later study [8], the same group reported depressed right ventricular activity due to increased right ventricular afterload by constricting pulmonary arteries in dogs with low blood ethanol levels...

    Tony Fracassoet al. Immunohistochemical expression of fibronectin and C5b-9 in the myocard...

    • ... These men may have suffered from alcohol related direct myocardial toxicity that was severe enough to result in RV dilatation and to turn the LV response from cavity reduction to incipient cavity enlargement “normalising” the LV size. It is also possible that an excess of RV afterload caused by passive pulmonary hypertension resulting from alcohol related LV dysfunction may have contributed to RV dilatation. Furthermore, alcohol also may raise pulmonary artery pressure (and RV systolic load) by more direct though as yet unknown mechanisms....

    O A Kajanderet al. Dose dependent but non-linear effects of alcohol on the left and right...

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