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Nanobioimaging and sensing of infectious diseases

Nanobioimaging and sensing of infectious diseases,10.1016/j.addr.2009.11.014,Advanced Drug Delivery Reviews,Padmavathy Tallury,Astha Malhotra,Logan M

Nanobioimaging and sensing of infectious diseases   (Citations: 7)
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New methods to identify trace amount of infectious pathogens rapidly, accurately and with high sensitivity are in constant demand to prevent epidemics and loss of lives. Early detection of these pathogens to prevent, treat and contain the spread of infections is crucial. Therefore, there is a need and urgency for sensitive, specific, accurate, easy-to-use diagnostic tests. Versatile biofunctionalized engineered nanomaterials are proving to be promising in meeting these needs in diagnosing the pathogens in food, blood and clinical samples. The unique optical and magnetic properties of the nanoscale materials have been put to use for the diagnostics. In this review, we focus on the developments of the fluorescent nanoparticles, metallic nanostructures and superparamagnetic nanoparticles for bioimaging and detection of infectious microorganisms. The various nanodiagnostic assays developed to image, detect and capture infectious virus and bacteria in solutions, food or biological samples in vitro and in vivo are presented and their relevance to developing countries is discussed.
Journal: Advanced Drug Delivery Reviews - ADVAN DRUG DELIVERY REV , vol. 62, no. 4, pp. 424-437, 2010
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    • ...Nanosensors are not just tiny sensors, but devices that take advantage of the properties of novel nanomaterials to identify and measure new types of events in the nanoscale, such as chemical compounds in concentrations as low as one part per billion [17], [15], or the presence of virus or harmful bacteria [23], [19]...

    Josep Miquel Jornetet al. Information capacity of pulse-based Wireless Nanosensor Networks

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