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Characterisation of G8 human rotaviruses in Australian children with gastroenteritis

Characterisation of G8 human rotaviruses in Australian children with gastroenteritis,10.1016/j.virusres.2009.11.013,Virus Research,Dayna L. Swiatek,En

Characterisation of G8 human rotaviruses in Australian children with gastroenteritis   (Citations: 3)
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This study describes the characterisation of G8 rotavirus strains isolated from humans with acute gastroenteritis. Six G8 strains were detected in Australia between 2002 and 2008. Four were G8P[14] strains, one was G8P[8]+[14] and one was G8 P non-typeable. By polyacrylamide gel electrophoresis and enzyme immunoassay analysis, four G8 strains with visible RNA exhibited a long electropherotype and five G8 strains displayed subgroup I specificity. Sequence analysis of the VP7 gene indicated that the G8 strains exhibited the highest nucleotide and amino acid identity with a G8P[11] bovine rotavirus strain detected in Japan. VP4 sequence data of one G8P[14] strain revealed that the closest identity was to another human-bovine-like strain detected in Australia, MG6, a G6P[14] strain. The identification of G8 strains causing disease further extends the number of G8P[14] strains detected in Australian children, and indicates that there is a rare but ongoing presence of uncommon human strains within the community in Australia.
Journal: Virus Research - VIRUS RES , vol. 148, no. 1, pp. 1-7, 2010
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