Academic
Publications
Genetic Diversity of Hantaviruses Isolated in China and Characterization of Novel Hantaviruses Isolated from Niviventer confucianus and Rattus rattus

Genetic Diversity of Hantaviruses Isolated in China and Characterization of Novel Hantaviruses Isolated from Niviventer confucianus and Rattus rattus,

Genetic Diversity of Hantaviruses Isolated in China and Characterization of Novel Hantaviruses Isolated from Niviventer confucianus and Rattus rattus   (Citations: 41)
BibTex | RIS | RefWorks Download
The antigenic and genetic properties of 46 hantaviruses from China, 13 from patients, 23 from rodents, and 10 from unknown hosts, were compared with those of other hantaviruses. The viruses were classified as either Hantaan (HTN) or Seoul (SEO) viruses. A phylogenetic analysis of the partial M (300 bp) and S (around 485 bp) genomes of HTN viruses identified nine distinct genetic subtypes, one consisting of isolates from Korea. The SEO viruses were divided into five genetic subtypes, although they had less variability than the HTN subtypes. There was a correlation between the subtype and province of origin for four subtypes of HTN viruses, confirming geographical clustering. Hantaan virus NC167 isolated from Niviventer confucianus and SEO virus Gou3 isolated from Rattus rattus were the basal clades in each virus. The phylogenetic trees constructed from the entire S and M segments suggested that NC167 was introduced to N. confucianus in a host-switching event. The reactivity of a panel of 35 monoclonal antibodies was almost exactly the same in NC167 and a representative HTN virus and in Gou3 and a representative SEO virus. However, there was a one-way cross-neutralization between them. These results confirm the varied nature of Murinae-associated hantaviruses in China.
Journal: Virology , vol. 278, no. 2, pp. 332-345, 2000
Cumulative Annual
View Publication
The following links allow you to view full publications. These links are maintained by other sources not affiliated with Microsoft Academic Search.
    • ...A previous study described Da Bie Shan virus (DBSV), Nc167 strain, which was isolated from Niviventer confucianus [16]...

    H.-R. Xionget al. Specific humoral reaction of hemorrhagic fever with renal syndrome (HF...

    • ...Also several provisional species have been described: Da Bie Shan virus in Nivivevnter confucianus [9], Gou virus in Rattus rattus [9], Vladivostok virus (VLAV) in M. fortis [10], Amur/Soochong virus in Apodemus peninsulae [11,12], and Muju virus (MUJV) in Myodes regulus [13]...
    • ...Also several provisional species have been described: Da Bie Shan virus in Nivivevnter confucianus [9], Gou virus in Rattus rattus [9], Vladivostok virus (VLAV) in M. fortis [10], Amur/Soochong virus in Apodemus peninsulae [11,12], and Muju virus (MUJV) in Myodes regulus [13]...

    Angelina Plyusninaet al. Genetic analysis of hantaviruses carried by Myodes and Microtus rodent...

    • ...[14]. A portion of the gene encoding the entire THAIV NP was amplified using the polymerase chain reaction (PCR) with the primers Bam_THLS46F (5 0 -GGATCCATGGCAA CTATGGAAGAG-3 0 ) and Bam_THLS1344R (5 0 -TGTGG GATCCTAGAGTTTTAA-3 0 ; the BamHI sites are shown in...
    • ...THAIV showed a typical THAIV infection reactivity pattern, while anti-SEOV immune sera against strains SR-11 (derived from Rattus norvegicus) and Gou3 [14] (derived from R. rattus) showed a typical SEOV infection reactivity...
    • ...Sera from laboratory rats immunized with SEOV strain SR-11 or Gou3 were prepared previously [14], and serum from rats immunized with THAIV and non-immunized rat serum (NRS) were used for serotyping ELISA (upper left)...
    • ...The lower panel shows immune mouse sera to THAIV strain thai749, HTNV strain 76118 [14], DBSV strain NC167 [14], and SEOV strain SR-11 [14]...
    • ...The lower panel shows immune mouse sera to THAIV strain thai749, HTNV strain 76118 [14], DBSV strain NC167 [14], and SEOV strain SR-11 [14]...
    • ...The lower panel shows immune mouse sera to THAIV strain thai749, HTNV strain 76118 [14], DBSV strain NC167 [14], and SEOV strain SR-11 [14]...
    • ...AMRV and other A. peninsulae-borne hantavirus from Korea (Soochong virus [22]) and China (lineage #2 [14]) were identified as distinct lineage from classical A. agrarius-borne HTNV...

    Ichiro Nakamuraet al. Development of a serotyping ELISA system for Thailand virus infection

    • ...Each hantavirus is associated with a specific host species, but occasional spillover infections in related rodents have been reported (Vincent et al., 2000; Wang et al., 2000)...

    Piet Maeset al. Evaluation of the efficacy of disinfectants against Puumala hantavirus...

Sort by: