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Propylene glycol and contact-lens solutions containing this diol induce pseudocyst formation in acanthamoebae

Propylene glycol and contact-lens solutions containing this diol induce pseudocyst formation in acanthamoebae,10.1016/j.exppara.2010.08.014,Experiment

Propylene glycol and contact-lens solutions containing this diol induce pseudocyst formation in acanthamoebae   (Citations: 1)
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Propylene glycol used as an ophthalmic demulcent in certain contact-lens care systems has been included recently among factors responsible for increasing Acanthamoeba keratitis. In this study, we provide evidence that propylene glycol as well as examined contact-lens solutions containing it induce rapid differentiation of acanthamoebae into pseudocysts. The partial resistance of the pseudocysts and their reversibility to viable trophozoites even after 24-h exposure to the contact-lens solutions indicate a potential risk of infection to contact-lens users.
Journal: Experimental Parasitology - EXP PARASITOL , vol. 127, no. 1, pp. 326-328, 2011
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