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Deletions of chromosomal regions coding for fimbriae and hemolysins occur in vitro and in vivo in various extra intestinal Escherichia coli isolates

Deletions of chromosomal regions coding for fimbriae and hemolysins occur in vitro and in vivo in various extra intestinal Escherichia coli isolates,1

Deletions of chromosomal regions coding for fimbriae and hemolysins occur in vitro and in vivo in various extra intestinal Escherichia coli isolates   (Citations: 84)
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Journal: Microbial Pathogenesis - MICROB PATHOG , vol. 8, no. 3, pp. 213-225, 1990
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    • ...GEIs play a major role in the fast and dramatic adaptation of species phenotypes to different environments by carrying clusters of genes that can cooperate to confer a cell with novel and useful phenotypes, such as the ability to survive inside a host. GEIs are large genomic regions that present deviations in codon usage, G+C content or dinucleotide frequency compared to other parts of the organism's genome; these characteristics are hallmarks of chromosome regions that were acquired horizontally from other species in a single block. GEIs are often flanked by insertion sequences or tRNA genes and transposase coding genes; these segments are responsible for the genomic incorporation of alien DNA obtained through transformation, conjugation or bacteriophage infection ...

    Siomar C. Soareset al. PIPS: Pathogenicity Island Prediction Software

    • ...The studies of GIs are very important to biomedical research, due to the fact that such knowledge can be used to explain why some strainsof bacteria within the same species are pathogenic while others are not [2], or the phenomena that some strains of bacteria can adapt to extreme environments while others cannot...

    Han Wanget al. An Integrative Approach for Genomic Island Prediction in Prokaryotic G...

    • ...gov/sites/entrez?Db=genomeprj&cmd=ShowDetailView&TermToSearch=12319">Escherichia coli strains but absent in the genomes of other...

    Morgan G. I. Langilleet al. Detecting genomic islands using bioinformatics approaches

    • ...Depending on the genetic elements of these genes, GIs can be sub-categorized into (a) pathogenicity islands (PAIs), where genes encode for virulence factors [1]; (b) metabolic islands (i.e., genes encode adaptive metabolic properties) [2]; (c) antibiotic islands (encode antibiotic resistance genes); or (d) secretion islands (encode secretion system genes) [3]...

    Dongsheng Cheet al. Classification of genomic islands using decision trees and their ensem...

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