Author | Conference | Journal | Organization | Year | DOI
Look for results that meet for the following criteria:
Academic
Publications
Divergence Time and Population Size in the Lineage Leading to Modern Humans

Divergence Time and Population Size in the Lineage Leading to Modern Humans,10.1006/tpbi.1995.1026,Theoretical Population Biology,N. Takahata,Y. Satta

Edit
Divergence Time and Population Size in the Lineage Leading to Modern Humans   (Citations: 95)
BibTex | RIS | RefWorks Download
We have developed maximum likelihood (ML) methods for comparisons of nucleotide sequences from unlinked genomic regions. In the case of a single species, the ML method primarily estimates the effective population size (Ne) under both constant size and abrupt expansion conditions. In the case of two or three species, the ML method simultaneously estimates the species divergence time and the effective size of ancestral populations. This allows us to trace the evolutionary history of the human population over the past several million years (my). Available sequences at human autosomal loci indicate Ne = 10,000 in the Late Pleistocene, a figure concordant with the results obtained from mitochondrial DNA sequence and allele-frequency data analysis, and there is no indication of population expansion. The ML analysis of two species shows that humans diverged from chimpanzees 4.6 my ago and that the human and chimpanzee clade diverged from the gorilla 7.2 my ago. Furthermore, the effective population size of humans more than 4.6 my ago is nearly 10 times larger than Ne of modern humans. The effective population size in the human lineage does not seem to have remained constant over the past several million pears. The ML model for three species predicts slightly different, but consistent results to those obtained by the two-species analysis.
Journal: Theoretical Population Biology - THEOR POP BIOL , vol. 48, no. 2, pp. 198-221, 1995
Cumulative Annual
View Publication
The following links allow you to view full publications. These links are maintained by other sources not affiliated with Microsoft Academic Search.
Sort by:

Citations (95)

Share this on