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Keywords
(2)
Insulin Resistant
Protein Kinase B
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S-Nitrosylation-dependent Inactivation of Akt/Protein Kinase B in Insulin Resistance
S-Nitrosylation-dependent Inactivation of Akt/Protein Kinase B in Insulin Resistance,10.1074/jbc.M411871200,Journal of Biological Chemistry,T. Yasukaw
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S-Nitrosylation-dependent Inactivation of Akt/Protein Kinase B in Insulin Resistance
(
Citations: 48
)
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T. Yasukawa
Journal:
Journal of Biological Chemistry - J BIOL CHEM
, vol. 280, no. 9, pp. 7511-7518, 2004
DOI:
10.1074/jbc.M411871200
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www.jbc.org
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Citation Context
(10)
...Third, antioxidant administration or iNOS inhibition may reverse insulin insensitivity in a variety of animal models of insulin resistance [6, 7]. It has been suggested that ROS- or nitric oxide-induced defects of insulin signalling are due to direct impairment of insulin signalling molecules by protein oxidation or nitrosylation [
8
, 9]. Several signalling abnormalities caused by alteration of redox homeostasis may also indirectly impair ...
Z. Yu
,
et al.
Oltipraz upregulates the nuclear respiratory factor 2 alpha subunit (N...
...et al., 2002; Fujimoto et al., 2005) and its complications (Ceriello et al., 2002), and alterations in the amount of Snitrosated proteins such as insulin receptors, insulin receptor substrate 1, and Akt (Carvalho-Filho et al., 2005;
Yasukawa et al., 2005;
Wadham et al., 2007) are reported to be involved in these diseases...
Xu Zhang
,
et al.
Quantitative proteomic analysis of S -nitrosated proteins in diabetic ...
...regulates this kinase has however not been investigated so far although Akt has been reported to be S-nitrosated in diabetic mice and in response to NO donors
...
Alfredo Csibi
,
et al.
Angiotensin II Inhibits Insulin-Stimulated GLUT4 Translocation and Akt...
...Oxidized SNAP (100 μM), which no longer releases NO [
47
], produced no significant activation of any potassium current either in SS (NPo = 102.3 ± 9.2% from baseline) or in SNL group (NPo = 97.0 ± 7.9% from baseline; n = 4 in each group)...
...Oxidized SNAP, that no longer generates NO, was prepared as described previously, by allowing SNAP dissolved in DMSO, to decompose at room temperature for 48 hours [
47
]...
Takashi Kawano
,
et al.
Nitric oxide activates ATP-sensitive potassium channels in mammalian s...
...S-nitrosylation of IRβ and Akt was associated with reductions in their kinase activities, leading to downregulation of the IRβ/IRS-1/PI 3kinase/Akt pathway [9,
30
]...
...nitrosylation of Akt is a specific post-translational modification that regulates its activity [
30
]...
M. A. Carvalho-Filho
,
et al.
Aspirin attenuates insulin resistance in muscle of diet-induced obese ...
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Citations
(48)
Ghrelin suppression of Helicobacter pylori -induced S -nitrosylation-dependent Akt inactivation exerts modulatory influence on gastric mucin synthesis
(
Citations: 1
)
B. L. Slomiany
,
A. Slomiany
Journal:
Inflammopharmacology
, vol. 19, no. 2, pp. 89-97, 2011
Offering People a Choice for Colorectal Cancer Screening. Attendance and Detection Rate in Turin and Verona
Luca Benazzato
,
Carlo Senore
,
Nereo Segnan
,
Paolo Inturri
,
Franca Patrizi
,
Massimo Valsecchi
,
Maria C. Chioffi
,
Ephrem Ntakirutinama
,
Mariella Molaro
,
Sofia Bencivenni
,
Alberto Fantin
,
Andrea Ederle
Journal:
Gastroenterology
, vol. 140, no. 5, pp. S-408-S-408, 2011
Oltipraz upregulates the nuclear respiratory factor 2 alpha subunit (NRF2) antioxidant system and prevents insulin resistance and obesity induced by a high-fat diet in C57BL/6J mice
Z. Yu
,
W. Shao
,
Y. Chiang
,
W. Foltz
,
Z. Zhang
,
W. Ling
,
I. G. Fantus
,
T. Jin
Journal:
Diabetologia
, vol. 54, no. 4, pp. 922-934, 2011
Relationship Among Colorectal Cancer, Advanced Histology and Polyp Size in Patients Undergoing Screening Colonoscopy in North Eastern Italy
Marco Marino
,
Elena Zucchi
,
Giovanni Terrosu
,
Debora Berretti
,
Ilva Lodolo
,
Roberto Maieron
,
Maurizio Zilli
Journal:
Gastroenterology
, vol. 140, no. 5, pp. S-415-S-415, 2011
Interval Cancers in a National Guaiac-Based FOBT Screening Programme
Robert J. Steele
,
Frank A. Carey
,
Callum G. Fraser
Journal:
Gastroenterology
, vol. 140, no. 5, pp. S-406-S-406, 2011