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Pharmacological Characterization of Pannexin-1 Currents Expressed in Mammalian Cells

Pharmacological Characterization of Pannexin-1 Currents Expressed in Mammalian Cells,10.1124/jpet.108.146365,Journal of Pharmacology and Experimental

Pharmacological Characterization of Pannexin-1 Currents Expressed in Mammalian Cells   (Citations: 15)
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    • ... This could be also the case with respect to the regulation of Panx1 channels by stomatin. Because stomatin coimmunoprecipitated with Panx1 carboxyl terminal and its inhibitory effect on Panx1 channels was abolished by deleting the carboxyl terminal of Panx1, stomatin probably regulates channel gating through interacting with the Panx1 carboxyl terminal. This notion is compatible with the previous observation that appending GFP to the carboxyl terminus of Panx1 reduces Panx1 channel currents ...

    Haiying Zhanet al. Stomatin Inhibits Pannexin-1-Mediated Whole-Cell Currents by Interacti...

    • ...For example, the human PANX1 and PANX2 genes have recently been reported to be differentially spliced (Baranova et al., 2004; Ma et al., 2008), generating two splice variants of each protein, and PANX1a and b seem to have unique expression patterns (Ma et al., 2008)...
    • ...For example, the human PANX1 and PANX2 genes have recently been reported to be differentially spliced (Baranova et al., 2004; Ma et al., 2008), generating two splice variants of each protein, and PANX1a and b seem to have unique expression patterns (Ma et al., 2008)...

    Silvia Penuelaet al. Glycosylation Regulates Pannexin Intermixing and Cellular Localization

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