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Immunostimulation Effect of Jellyfish Collagen

Immunostimulation Effect of Jellyfish Collagen,10.1271/bbb.60076,Bioscience Biotechnology and Biochemistry,Takuya SUGAHARA,Masashi UENO,Yoko GOTO,Ryus

Immunostimulation Effect of Jellyfish Collagen   (Citations: 8)
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Journal: Bioscience Biotechnology and Biochemistry - BIOSCI BIOTECHNOL BIOCHEM , vol. 70, no. 9, pp. 2131-2137, 2006
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    • ...Recent studies have confirmed that jellyfish collagen suppresses arthritis in laboratory rats [56] and stimulates autoimmune and inflammatory responses in humans [61], but most traditional medicinal uses remain untested...

    Anthony J. Richardsonet al. The jellyfish joyride: causes, consequences and management responses t...

    • ...We found that jellyfish extracts enhanced IgM production by HB4C5 cells 34-fold (Sugahara et al. 2006)...
    • ...In addition, collagens from bovine Achilles’ tendon and rat tail showed stimulated IgM production of HB4C5 cells (Sugahara et al. 2006)...
    • ...Collagenase treatment of the extracts completely inactivated the Ig production stimulation effects on HB4C5 cells, and Achilles tendon collagen activates Ig production of the cells (Sugahara et al. 2006)...
    • ...As we have reported earlier, jellyfish collagen extracts stimulates Ig production by human hybridoma cells and hPBLs (Sugahara et al. 2006)...
    • ...Jellyfish collagen extracts enhanced the production of IgM by human hybridoma HB4C5 cells, and that of IgM, IgG, IFN-c, and TNF-a by hPBLs (Sugahara et al. 2006)...
    • ...Our previous data show that purified collagen from bovine Achilles’ tendon stimulated IgM production by human hybridoma HB4C5 cells (Sugahara et al. 2006)...

    Hitoshi Morishigeet al. Immunostimulatory effects of collagen from jellyfish in vivo

    • ...After cultivating for 6 h in a CO2 incubator at 37°C, the amount of IgM secreted into each culture medium was determined by an enzyme-linked immunosorbent assay (ELISA) which was performed by using an anti-human IgM antibody (Biosource International) as described in a previous report (Sugahara et al., 2006)...

    Takuya SUGAHARAet al. The StructureActivity Relationships of Flaxseed Lignan, Secoisolaricir...

    • ...ELISA was performed as a previously described [12, 13]...

    Sogo Nishimotoet al. The Effects of Pesticides on Immune Cells

    • ...ELISA was performed as previously described (Sugahara et al., 2006;...

    Sogo NISHIMOTOet al. Abnormal Response Induced by Pesticides on Mammalian Immune System

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