Academic
Publications
Resveratrol bioavailability and toxicity in humans

Resveratrol bioavailability and toxicity in humans,10.1002/mnfr.200900437,Molecular Nutrition & Food Research,Charles-Henry Cottart,Christelle Laguill

Resveratrol bioavailability and toxicity in humans   (Citations: 21)
BibTex | RIS | RefWorks Download
Journal: Molecular Nutrition & Food Research - MOL NUTR FOOD RES , vol. 54, no. 1, pp. 7-16, 2010
Cumulative Annual
View Publication
The following links allow you to view full publications. These links are maintained by other sources not affiliated with Microsoft Academic Search.
    • ...Resveratrol is a grape-derived polyphenol, which possesses a wide range of bioactivities including antioxidant, anti-inflammatory and anti-tumor effects (Weng et al, 2010; Cottart et al, 2010)...

    Jianbo Xiaoet al. Advance in dietary polyphenols as α-glucosidases inhibitors: a review ...

    • ...In addition, this polyphenol is well tolerated, and no harmful effects have been reported (3,4)...
    • ...The pharmacokinetic (PK) information existing for transresveratrol to date is limited despite that different studies have assessed its oral bioavailability both in animals and humans (4)...
    • ...As a result of this complex interplay between enzyme activities and efflux transporters, the concentrations of trans-resveratrol in plasma have been reported to be low (4)...
    • ...The metabolism in the liver accounted for an extensive glucuronidation and sulfatation through UDP-glucuronosyltransferase (UGT) and sulfotransferase, respectively (4,27)...
    • ...TVCL1 = THETA(1) CL1 = TVCL1*EXP(ETA(1)) ;Plasmatic CL of resveratrol V2 = THETA(2) ;Central compartment V of resveratrol Q = THETA(3)*EXP(ETA(2)) ;Distributional CL of resveratrol V3 = THETA(4) ;Peripheral compartment V of resveratrol ;Glucuronide V4 = 0.05 ;Central compartment V of the glucuronide QM1 = THETA(5) ;Distributional CL of the glucuronide V5 = THETA(6) *EXP(ETA(3)) ;Peripheral compartment V of the glucuronide FM = THETA(7) ...

    Helena Colomet al. Population Pharmacokinetic Modeling of trans- Resveratrol and Its Gluc...

    • ...The validity of information obtained in primates, particularly in humans, is still under debate because the experimental protocols used in the preliminary studies were quite different from each other [9]...

    Alexandre Dal-Panet al. Resveratrol suppresses body mass gain in a seasonal non-human primate ...

    • ...Trans-resveratrol can be readily converted to cis-resveratrol when exposed to UV light and is unstable when exposed to high pH. In addition to resveratrol isomers, derivatives of resveratrol that include its glucosylated, prenylated, methylated, and hydroxylated modifications have been linked with beneficial activities [19, 20]...

    Giulia Lanzilliet al. Anti-inflammatory Effect of Resveratrol and Polydatin by In Vitro IL17...

Sort by: