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Y chromosome sequence variation and the history of human populations

Y chromosome sequence variation and the history of human populations,10.1038/81685,Nature Genetics,Peidong Shen,Alice A. Lin,Li Jin,Giuseppe Passarino

Y chromosome sequence variation and the history of human populations   (Citations: 365)
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Peidong Shen, Alice A. Lin, Li Jin, Giuseppe Passarino, Wei H. Yang, Erin Kauffman, Batsheva Bonné-Tamir, Jaume Bertranpetit, Paolo Francalacci, Muntaser Ibrahim, Trefor Jenkins, Judith R. Kiddhttp://academic.research.microsoft.com/io.ashx?type=5&id=4107164&selfId1=0&selfId2=0&maxNumber=12&query=
Binary polymorphisms associated with the non-recombining region of the human Y chromosome (NRY) preserve the pater- nal genetic legacy of our species that has persisted to the pre- sent, permitting inference of human evolution, population affinity and demographic history1. We used denaturing high- performance liquid chromatography (DHPLC; ref. 2) to identify 160 of the 166 bi-allelic and 1 tri-allelic site that formed a parsi- monious genealogy of 116 haplotypes, several of which display distinct population affinities based on the analysis of 1062 globally representative individuals. A minority of contempo- rary East Africans and Khoisan represent the descendants of the most ancestral patrilineages of anatomically modern humans that left Africa between 35,000 and 89,000 years ago.
Journal: Nature Genetics - NAT GENET , vol. 26, no. 3, pp. 358-361, 2000
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