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Keywords
(5)
Antioxidant Activity
Catalase
Human Health
Iron
of Hydroxyl Radicals
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Characterization of food antioxidants, illustrated using commercial garlic and ginger preparations
Characterization of food antioxidants, illustrated using commercial garlic and ginger preparations,10.1016/S0308-8146(95)00254-5,Food Chemistry,Okezie
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Characterization of food antioxidants, illustrated using commercial garlic and ginger preparations
(
Citations: 25
)
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Okezie I. Aruoma
,
Jeremy P. E. Spencer
,
Donna Warren
,
Peter Jenner
,
John Butler
,
Barry Halliwell
Methods for the characterization of antioxidants are presented and illustrated by their application to commercial garlic and ginger preparations, since it has been widely speculated that garlic and ginger might be beneficial to
human health
because they exert ‘antioxidant activity’. The sample of commercial ginger powder, tested at concentrations up to 5 mg/ml, inhibited the peroxidation of phospholipid liposomes, but a sample of one commercial garlic preparation was less effective. Both preparations could scavenge peroxyl radicals, but the garlic preparation was again less effective.The ginger and garlic preparations were powerful scavengers
of hydroxyl radicals
(OH) and were able to react with hypochlorous acid (HOCl) at a rate sufficient to protect
catalase
and alpha-l-antiproteinase against inactivation. However, they could also interact with
iron
chelates to facilitate OH generation from H2O2 (‘pro-oxidant’ activity). Ginger (but not the garlic preparation) also exerted pro-oxidant action in the bleomycin assay, accelerating damage to DNA in the presence of a bleomycin-ferric
iron
complex.Our results illustrate the use of antioxidant characterization methods.
Journal:
Food Chemistry - FOOD CHEM
, vol. 60, no. 2, pp. 149-156, 1997
DOI:
10.1016/S0308-8146(95)00254-5
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Citation Context
(3)
...Hollman
et al
, 1996;
...
R Pulido
,
et al.
Contribution of beverages to the intake of lipophilic and hydrophilic ...
...-EDTA complex, which represents its ability to stimulate hydroxyl radical generation (
Aruoma et al., 1997
), was not observed when high concentrations of REEE-1 were added (Table 1). This indicates that the pro-oxidant activity of REEE-1 was readily overwhelmed by the anti-oxidant potential of the extract...
Jeong-Chae Lee
,
et al.
Ethanol-eluted Extract of Rhus verniciflua Stokes Inhibits Cell Growth...
...whether the extract concentration influences antioxidant activity or if a prooxidant effect occurs (2,
7
)...
...The polarity of the system (7‐9), the presence of metals (
7
,8,10), and the use of either too low (8,11) or too high a concentration of antioxidants (12) can influence this behavior...
Andrés Moure
,
et al.
Simulation of multistage extraction of antioxidants from Chilean hazel...
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Citations
(25)
Brazilian Ginseng extraction via LPSE and SFE: Global yields, extraction kinetics, chemical composition and antioxidant activity
Patrícia F. Leal
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Marina B. Kfouri
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Fábio C. Alexandre
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Study on Microwave-Assisted Extract and Antioxidant Activity of Ginger Flavonoids
Liu Ling-ling
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Lou Lun-jiao
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Nie Jian-qi
Conference:
International Conference on Bioinformatics and Biomedical Engineering - ICBBE
, pp. 1-4, 2010
The effect of citric acid on the phenolic contents of olive oil
(
Citations: 6
)
Bahar Aliakbarian
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Journal:
Food Chemistry - FOOD CHEM
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Chemical composition, antioxidative activity and cell viability effects of a Siberian pine ( Pinus sibirica Du Tour) extract
(
Citations: 1
)
Tiina A. Lantto
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H. J. Damien Dorman
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Alexander N. Shikov
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Olga N. Pozharitskaya
,
Valery G. Makarov
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Vladimir P. Tikhonov
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Raimo Hiltunen
,
Atso Raasmaja
Journal:
Food Chemistry - FOOD CHEM
, vol. 112, no. 4, pp. 936-943, 2009
Antiapoptotic effects of dietary antioxidants towards N -nitrosopiperidine and N -nitrosodibutylamine-induced apoptosis in HL60 and HepG2 cells
(
Citations: 1
)
Almudena García
,
Paloma Morales
,
Nuria Arranz
,
Ma Eugenia Delgado
,
Joseph Rafter
,
Ana I. Haza
Journal:
Journal of Applied Toxicology - J APPL TOXICOL
, vol. 29, no. 5, pp. 403-413, 2009