Computationally effi - cient cardiac bioelectricity models toward whole - heart simulation
Abstract— This paper studies the characteristics of excitable cell mathematical models, with the goal of developing new insights and techniques in simulating the electrical behavior of the human,heart. While very simple models of such behavior can be simulated at real-time or better speeds on powerful computing equipment, the use of realistic cell models or organmagnitude cell networks make the simulations computationally infeasible. We present an examination of the FitzHugh-Nagumo model and its response to stimulus and, in order to move toward the goal of a full cardiac simulation, we present a method of optimizing single-cell calculations through local interpolation techniques. Additionally, we introduce a separate method of optimizing multi-cell simulations by tracking cellular activations. Keywords— cardiac bioelectricity modeling, FitzHugh-
Published in 2004.