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Prenatal Exposure to PBDEs and Neurodevelopment

Prenatal Exposure to PBDEs and Neurodevelopment,10.1289/ehp.0901340,Environmental Health Perspectives,Julie B. Herbstman,Andreas Sjödin,Matthew Kurzon

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    • ...Higher cord blood PBDE was significantly associated with decreased scores for mental and motor neurodevelopment in children between 1 and 4 years [142]...

    SYAM S. ANDRAet al. Thyroid Disrupting Chemicals in Plastic Additives and Thyroid Health

    • ...We also note that the concentrations in this sample are, to our knowledge, higher than previously reported in any other population, even from the 2003- 2004 NHANES sample [34], and are seven to ten times higher than those reported to predict lower cognitive scores in a sample of children from New York City [35]...
    • ...remain high; data from animals [11,14] and humans [35] have shown neurodevelopmental effects following prenatal exposures; and experimental research suggests several relevant mechanisms of toxicity [15,22-25]...

    Irva Hertz-Picciottoet al. Polybrominated diphenyl ethers in relation to autism and developmental...

    • ...An important cause for concern regarding organohalogen toxicants is their possible association with lower IQ scores in childhood following perinatal exposure (Jacobson and Jacobson 1996; Herbstman et al...

    Margarita C. Currás-Collazo. Nitric Oxide Signaling as a Common Target of Organohalogens and Other ...

    • ...Herbstman et al. (2010) showed that children with higher PBDE concentrations had lower scores of mental and motor development at one to four and six years [9]...

    Ding-Yan Linet al. Infants ingesting high breast milk levels of polybrominated diphenyl e...

    • ...In an effort to follow-up on animal studies suggesting neurodevelopmental effects following exposures to PBDEs, Herbstman et al. [27] conducted a prospective cohort study to evaluate the potential associations between prenatal exposure to PBDEs and neurodevelopment...
    • ...The findings reported by Herbstman et al. [27] are consistent with toxicological data published in animal studies, thus lending confidence to these findings with the support of biological plausibility...
    • ...However, not all trends observed in animal studies were observed by Herbstman et al. [27], suggesting differential mechanisms and/or effects between species...

    Daniele Staskal Wikoffet al. Human Health Effects of Brominated Flame Retardants

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