The role of salt abuse on risk for hypercalciuria

The role of salt abuse on risk for hypercalciuria,10.1186/1475-2891-10-3,Nutrition Journal,Patrícia CG Damasio,Carmen RPR Amaro,Natália B Cunha,Ana C

The role of salt abuse on risk for hypercalciuria   (Citations: 1)
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Background  Elevated sodium excretion in urine resulting from excessive sodium intake can lead to hypercalciuria and contribute to the formation of urinary stones. The aim of this study was to evaluate salt intake in patients with urinary lithiasis and idiopathic hypercalciuria (IH). Methods  Between August 2007 and June 2008, 105 lithiasic patients were distributed into 2 groups: Group 1 (n = 55): patients with IH (urinary calcium excretion > 250 mg in women and 300 mg in men with normal serum calcium); Group 2 (n = 50): normocalciuric patients (NC). Inclusion criteria were: age over 18 years, normal renal function (creatinine clearance ≥ 60 ml/min), absent proteinuria and negative urinary culture. Pregnant women, patients with intestinal pathologies, chronic diarrhea or using corticoids were excluded. The protocol of metabolic investigation was based on non-consecutive collection of two 24-hour samples for dosages of: calcium, sodium, uric acid, citrate, oxalate, magnesium and urinary volume. Food intake was evaluated by the three-day dietary record quantitative method, and the Body Mass Index (BMI) was calculated and classified according to the World Health Organization (WHO). Sodium intake was evaluated based on 24-hour urinary sodium excretion. Results  The distribution in both groups as regards mean age (42.11 ± 10.61 vs. 46.14 ± 11.52), weight (77.14 ± 16.03 vs. 75.99 ± 15.80), height (1.64 ± 0.10 vs. 1.64 ± plusorminus 0.08) and BMI (28.78 ± 5.81 vs. 28.07 ± 5.27) was homogeneous. Urinary excretion of calcium (433.33 ± 141.92 vs. 188.93 ± 53.09), sodium (280.08 ± 100.94 vs. 200.44.93 ± 65.81), uric acid (880.63 ± 281.50 vs. 646.74 ± 182.76) and magnesium (88.78 ± 37.53 vs. 64.34 ± 31.84) was significantly higher in the IH group (p < 0.05). There was no statistical difference in calcium intake between the groups, and there was significantly higher salt intake in patients with IH than in NC. Conclusions  This study showed that salt intake was higher in patients with IH as compared to NC.
Journal: Nutrition Journal - NUTR J , vol. 10, no. 1, pp. 1-4, 2011
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    • ...Although the focus of our article in Nutrition Journal [1] reports some novel data and has a different focus compared to our publication in the International Brazilian Journal of Urology [2], we acknowledge that we have duplicated some text and results and that our Nutrition Journal article reports outcome data from the same study population...
    • ...Since publication of this article [1], it has come to our attention that there is an error in the section discussing assumptions about obesity-related costs...

    Patrícia Capuzzo Garcia Damasioet al. Correction: The role of salt abuse on risk for hypercalciuria

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