Pathogenesis of HIV in the Central Nervous System

Pathogenesis of HIV in the Central Nervous System,10.1007/s11904-010-0070-4,Current Hiv/aids Reports,Victor Valcour,Pasiri Sithinamsuwan,Scott Letendr

Pathogenesis of HIV in the Central Nervous System   (Citations: 3)
BibTex | RIS | RefWorks Download
HIV can infect the brain and impair central nervous system (CNS) function. Combination antiretroviral therapy (cART) has not eradicated CNS complications. HIV-associated neurocognitive disorders (HAND) remain common despite cART, although attenuated in severity. This may result from a combination of factors including inadequate treatment of HIV reservoirs such as circulating monocytes and glia, decreased effectiveness of cART in CNS, concurrent illnesses, stimulant use, and factors associated with prescribed drugs, including antiretrovirals. This review highlights recent investigations of HIV-related CNS injury with emphasis on cART-era neuropathological mechanisms in the context of both US and international settings.
Journal: Current Hiv/aids Reports - CURR HIV AIDS REP , vol. 8, no. 1, pp. 54-61, 2011
Cumulative Annual
View Publication
The following links allow you to view full publications. These links are maintained by other sources not affiliated with Microsoft Academic Search.
Sort by: