Author | Conference | Journal | Organization | Year | DOI
Look for results that meet for the following criteria:
Academic
Publications
Molecular characterization reveals involvement of altered el tor biotype Vibrio cholerae O1 strains in cholera outbreak at Hyderabad, India

Molecular characterization reveals involvement of altered el tor biotype Vibrio cholerae O1 strains in cholera outbreak at Hyderabad, India,10.1007/s1

Edit
Molecular characterization reveals involvement of altered el tor biotype Vibrio cholerae O1 strains in cholera outbreak at Hyderabad, India  
BibTex | RIS | RefWorks Download
Thirty-four Vibrio cholerae isolates collected from a cholera outbreak in Hyderabad, South India were found to belong to serogroup Ol biotype El Tor serotype Ogawa. The genotype of all the isolates was confirmed by PCR assays. All the isolates were found PCR positive for ctxAB, ompW, rflOl, rtxC, and tcpA genes. All the isolates but one harboured rstR El Tor allele. However, one isolate carried both rstR EL Tor as well as rstR Classical alleles. Cholera toxin (ctxB) genotyping of the isolates confirmed the presence of altered cholera toxin B of classical biotype in all the isolates. All the isolates except VCH35 harboured an RS1-CTX prophage array on the large chromosome. The isolate VCH35 contained a tandem repeat of classical CTX prophage on the small chromosome. The clonal relationship among the V. cholerae isolates as carried out by enterobacterial repetitive intergenic consensus sequences PCR, BOX PCR and randomly amplified polymorphic DNA, uniformly showed a genetic relationship among the outbreak isolates. The results of this study suggest that altered El Tor biotype V. cholerae with the classical cholera toxin gene are involved in cholera outbreaks in India.
Journal: Journal of Microbiology - J MICROBIOL , vol. 49, no. 2, pp. 280-284, 2011
Cumulative Annual
View Publication
The following links allow you to view full publications. These links are maintained by other sources not affiliated with Microsoft Academic Search.
Share this on