Primary leiomyosarcoma of the breast treated by partial resection of the breast including nipple and areola: Report of a case
A 46-year-old female patient presented with a tumor measuring 0.5 cm in diameter under the areola of the breast. Because no
definite malignancy was found with inspection and palpation, imaging analysis, or with a fine-needle aspiration cytology examination,
follow-up observation was recommended. When the patient visited the hospital 6 months later, the mass was 0.9 cm in diameter.
The tumor was excised and histopathologically diagnosed as a leiomyosarcoma. Subsequently, the patient underwent a partial
resection of the breast, including the nipple and areola. A follow-up examination revealed no evidence of distant metastasis
or local recurrences 8 years 4 months after the surgery. Primary leiomyosarcoma of the breast is extremely rare. Only 33 cases,
which are reviewed in the present study, have been previously reported in the literature.