Academic
Publications
Lack of association between plasma myeloperoxidase levels and angiographic severity of coronary artery disease in patients with acute coronary syndrome

Lack of association between plasma myeloperoxidase levels and angiographic severity of coronary artery disease in patients with acute coronary syndrom

Lack of association between plasma myeloperoxidase levels and angiographic severity of coronary artery disease in patients with acute coronary syndrome  
BibTex | RIS | RefWorks Download
Objective  To evaluate the association between plasma myeloperoxidase (MPO) levels and angiographic severity of coronary atherosclerotic lesions in patients with non-ST elevation acute coronary syndrome (ACS). Design and methods  This cross-sectional study examined high-risk ACS patients who underwent coronary angiography within 72 h of the onset of symptoms by measuring their plasma MPO levels after sheath insertion. Gensini score was used to evaluate angiographic severity of coronary artery disease. Results  A total of 48 patients were included in the study. Median MPO levels and Gensini scores were 6.9 ng/mL (4.4–73.5 ng/mL) and 10 (0–87.5), respectively. Spearman’s correlation coefficient did not show a significant association between MPO levels and Gensini scores (r s = 0.2; p = 0.177). There was no correlation between MPO and age, hypertension, diabetes, leukocyte count, troponin I, CK-MB ≥2 × ULN (upper limit of normal), TIMI risk score ≥4 and Gensini score in the multivariate analysis. Conclusion  Our findings indicate that MPO expression is not associated with anatomical severity of coronary lesions in ACS.
Journal: Inflammation Research - INFLAMM RESEARCH , vol. 60, no. 2, pp. 137-142, 2011
Cumulative Annual
View Publication
The following links allow you to view full publications. These links are maintained by other sources not affiliated with Microsoft Academic Search.