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Single Transplanted Kidneys from A 90YearOld Deceased Donor Perform Acceptably at 1 Year

Single Transplanted Kidneys from A 90YearOld Deceased Donor Perform Acceptably at 1 Year,10.1016/j.transproceed.2011.01.192,Transplantation Proceeding

Single Transplanted Kidneys from A 90YearOld Deceased Donor Perform Acceptably at 1 Year  
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Most centers are reluctant to accept expanded criteria donors above 70 to 75 years of age. We accepted kidneys from a 90-year-old male and report the 1-year outcome. The kidneys were used as single transplants and both had immediate graft function. Recipient A was a 71-year-old male, with cold ischemia time of 4 hours 49 minutes. One rejection was successfully treated with intravenous methylprednisolone. At 1 year, serum creatinine was 146 μmol/L with estimated glomerular filtration rate (eGFR) 41 mL/min. Recipient B was a 79-year-old male with known panel-reactive antibody positivity prior to transplantation. Cold ischemia time was 10 hours 4 minutes. He experienced no rejections. At 1 year serum-creatinine was 99 μmol/L with eGFR 63 mL/min. Both recipients performed a surveillance biopsy at 1 year with identical findings: interstitial fibrosis and tubular atrophy grade 1 with moderate to severe arteriolosclerosis. We conclude that both kidneys performed acceptably 1 year after engraftment. The use of old kidneys in old recipients gives them a properly functioning kidney and improves quality of life. Longer observation is needed.
Journal: Transplantation Proceedings - TRANSPLANT PROC , vol. 43, no. 5, pp. 2107-2109, 2011
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