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Unresponsiveness to a Kidney Graft After a Fully Matched Allogenic Bone Marrow Transplantation Combined With Low-Dose Tacrolimus Therapy: A Case Report

Unresponsiveness to a Kidney Graft After a Fully Matched Allogenic Bone Marrow Transplantation Combined With Low-Dose Tacrolimus Therapy: A Case Repor

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Unresponsiveness to a Kidney Graft After a Fully Matched Allogenic Bone Marrow Transplantation Combined With Low-Dose Tacrolimus Therapy: A Case Report  
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We present the case of a patient with past medical history of acute mieloblastic leukemia treated with a related, fully match alogenic bone marrow transplantation (BMT). He presented after BMT treatment graft versus host disease (GVHD) and thrombotic thrombocytopenic purpura. He also developed end-stage renal disease that required renal replacement therapy. A preemptive kidney transplant was performed. The haematopoiesis were in complete chimera and the patient developed tolerance to the kidney graft, requiring only minimal immunossupression because of his GVHD.
Journal: Transplantation Proceedings - TRANSPLANT PROC , vol. 43, no. 6, pp. 2344-2346, 2011
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