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Study of HLA Class I gene in Indian schizophrenic patients of Siliguri, West Bengal

Study of HLA Class I gene in Indian schizophrenic patients of Siliguri, West Bengal,10.1016/j.psychres.2011.03.010,Psychiatry Research,Bisu Singh,Nirm

Study of HLA Class I gene in Indian schizophrenic patients of Siliguri, West Bengal  
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The authors studied the prevalence of the human leukocyte antigen (HLA) Class I gene in 136 (85 male, 51 female) India-born schizophrenia patients residing in and around the Siliguri subdivision of West Bengal by the PCR-SSP method. The control group consisted of 150 age- and sex-matched healthy individuals from the same ethnic group as the patients. Increased frequency of HLA A*03 as well as decreased frequencies of HLA A*31 and HLA B*51, was noted. The study suggests the possible existence of a susceptibility locus for schizophrenia within the HLA region.
Journal: Psychiatry Research - PSYCHIAT RES , vol. 189, no. 2, pp. 215-219, 2011
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