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Consolidation par 90Y-epratuzumab en fractionné dans le lymphome B diffus à grandes cellules : résultats préliminaires d’une étude de phase II

Consolidation par 90Y-epratuzumab en fractionné dans le lymphome B diffus à grandes cellules : résultats préliminaires d’une étude de phase II,10.1016

Consolidation par 90Y-epratuzumab en fractionné dans le lymphome B diffus à grandes cellules : résultats préliminaires d’une étude de phase II  
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A. Pallardy, P. Soubeyran, C. Bodet-Milin, H. Maisonneuve, S. Le Gouill, C. Rousseau, A. Faivre-Chauvet, A.-L. Cazeau, E. Garin, J.-L. Baulieu, A. Brion, J.-P. Vuillezhttp://academic.research.microsoft.com/io.ashx?type=5&id=49451475&selfId1=0&selfId2=0&maxNumber=12&query=
PurposeA multicenter, non-randomized, on-going phase II study, promoted by the GOELAMS aims to evaluate the efficacy and safety of fractionated administration of 90Y-epratuzumab (two injections 7days apart) in consolidation therapy for patients older than 60years with diffuse large B-cell lymphoma and large tumor mass who presented a complete response (CR), unconfirmed CR (uCR) or partial response (PR) after induction therapy with six courses of R-CHOP14. We report the preliminary results on 41 of the 75 enrolled patients.
Journal: Medecine Nucleaire-imagerie Fonctionnelle Et Metabolique - MED NUCL , vol. 35, no. 9, pp. 478-486, 2011
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