Author | Conference | Journal | Organization | Year | DOI
Look for results that meet for the following criteria:
Academic
Publications
Discovering genetic polymorphism associated with gene expression levels across the whole genome

Discovering genetic polymorphism associated with gene expression levels across the whole genome,10.1109/IEMBS.2009.5334061,Athos Antoniades,Ioanna Kal

Edit
Discovering genetic polymorphism associated with gene expression levels across the whole genome  
BibTex | RIS | RefWorks Download
Genetic differences have been shown to contribute to gene expression variability. A complete evaluation of the associations between a whole genome scan with 550 k Single Nucleotide Polymorphisms (SNPs) and 54 k detectable expression levels (probesets) was performed on 176 human peripheral blood samples. The results are presented along with visualizations that reveal cis and trans gene expression regulatory effects. The algorithmic approach followed utilized a distributed computational system. The analysis was performed using a linear regression adjusting for all relevant covariates. Permutation testing on a random subset of the top results provided an indication of the significance levels adjusted for multiple testing and the non independence of SNPs due to linkage disequilibrium. The database of the produced results can be used as a resource to assess the functional impact of genetic polymorphisms to gene expression regulation. This resource is applicable across all disease areas.
Conference: Annual International Conference of the IEEE Engineering in Medicine and Biology Society - EMBC , pp. 5466-5469, 2009
Cumulative Annual
View Publication
The following links allow you to view full publications. These links are maintained by other sources not affiliated with Microsoft Academic Search.
Share this on