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CMOS biosensor platform

CMOS biosensor platform,10.1109/IEDM.2010.5703484,F. Widdershoven,D. Van Steenwinckel,J. Überfeld,T. Merelle,H. Suy,F. Jedema,R. Hoofman,C. Tak,A. Se

CMOS biosensor platform  
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F. Widdershoven, D. Van Steenwinckel, J. Überfeld, T. Merelle, H. Suy, F. Jedema, R. Hoofman, C. Tak, A. Sedzin, B. Cobelens, E. Sterckx, R. van der Werfhttp://academic.research.microsoft.com/io.ashx?type=5&id=51017616&selfId1=0&selfId2=0&maxNumber=12&query=
The detection principle, process integration and system architecture of a novel 90-nm CMOS-based mixed-signal capacitive biosensor with 256 × 256 densely packed nano-electrodes are presented. The sensor operates at modulation frequencies up to 200 MHz, and has on-chip temperature sensors, A/D converters and digital I/O. Brownian motion of nanobeads over the sensor surface has been recorded in real time. The biosensor principle has been validated with a biological test assay. The sensor provides a versatile platform for a multitude of novel multiplexed biosensing applications with enhanced performance by digital control and statistical data analysis.
Conference: International Electron Devices Meeting - IEDM , pp. 36.1.1-36.1.4, 2010
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