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Point-and-Click Cursor Control With an Intracortical Neural Interface System by Humans With Tetraplegia

Point-and-Click Cursor Control With an Intracortical Neural Interface System by Humans With Tetraplegia,10.1109/TNSRE.2011.2107750,IEEE Transactions o

Point-and-Click Cursor Control With an Intracortical Neural Interface System by Humans With Tetraplegia  
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We present a point-and-click intracortical neural interface system (NIS) that enables humans with tetraplegia to volitionally move a 2-D computer cursor in any desired direc- tion on a computer screen, hold it still, and click on the area of interest. This direct brain-computer interface extracts both discrete (click) and continuous (cursor velocity) signals from a single small population of neurons in human motor cortex. A key component of this system is a multi-state probabilistic decoding algorithm that simultaneously decodes neural spiking activity of
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