Sign in
Author
|
Conference
|
Journal
|
Organization
|
Year
|
DOI
Look for results that meet for the following criteria:
since
equal to
before
between
and
Search in all fields of study
Limit my searches in the following fields of study
Agriculture Science
Arts & Humanities
Biology
Chemistry
Computer Science
Economics & Business
Engineering
Environmental Sciences
Geosciences
Material Science
Mathematics
Medicine
Physics
Social Science
Multidisciplinary
Related Publications
(3)
Cancer chronotherapy: Principles, applications, and perspectives
Relationship between Dihydropyrimidine Dehydrogenase Activity and Plasma 5-FluorouraciI Levels with Evidence for Orcadian Variation of Enzyme Activity and Plasma Drug Levels in Cancer Patients Receiving 5Fluorouracil by Protracted Continuous Infusion1
Host Circadian Clock as a Control Point in Tumor Progression
Subscribe
Academic
Publications
Circadian chronotherapy for human cancers
Circadian chronotherapy for human cancers,10.1016/S1470-2045(00)00326-0,Lancet Oncology,Francis Lévi
Edit
Circadian chronotherapy for human cancers
(
Citations: 39
)
BibTex
|
RIS
|
RefWorks
Download
Francis Lévi
Journal:
Lancet Oncology - LANCET ONCOL
, vol. 2, no. 5, pp. 307-315, 2001
DOI:
10.1016/S1470-2045(00)00326-0
Cumulative
Annual
View Publication
The following links allow you to view full publications. These links are maintained by other sources not affiliated with Microsoft Academic Search.
(
www.sciencedirect.com
)
(
linkinghub.elsevier.com
)
(
chrono-biology.net
)
(
rbc.vjf.inserm.fr
)
More »
Citation Context
(19)
...
2002
,
2004
) and dampens circadian rest-activity rhythm in patients with metastatic colorectal cancer (Lévi
1997
,
2001
; Mormont et al...
Saba Taj
,
et al.
Temporal profiles of physical activity and energy expenditure in cance...
...Several randomized clinical trials have demonstrated significant improvements in tolerability and antitumor efficacy of chemotherapy with standardized chronomodulated administrations in comparison with a constant rate infusion of chemotherapy
...
Samuel Bernard
,
et al.
Tumor Growth Rate Determines the Timing of Optimal Chronomodulated Tre...
...The underlying mechanisms for the temporal variation in chemotherapy could include circadian rhythms in various relevant rhythms, thiol concentrations, cell-cycle phase distribution and bone marrow progenitor cell counts (Bjarnason and Jordan
2000
; Levi
2001
)...
P. Subramanian
,
et al.
Role of biological clocks in cancer processes and chronotherapy
...For instance, least toxicity of 5-FU occurred near 0500 h after light onset in mice and was predicted to correspond to 0400 h in human subjects, resting from 2300 to 0700 h [
18
]...
...Using Programmable Pumps The clinical relevance of the chronotherapy principle was mainly tested in a large population of patients with metastatic colorectal cancer, using the standard methodology of clinical trials [
18
], [19]...
...This improvement in tolerability was accompanied with a significant increase in antitumor activity (objective response rate) from 29–51% [
18
], [20], [21]...
Francis Levi
.
The Circadian Timing System: A Coordinator of Life Processes [Chronobi...
...Such synchronization naturally relies on the circadian system and it has been in use in clinical [
22
], [27] and in theoretical [1], [9] settings in oncology with macroscopic modeling for drug delivery regimen and therapeutic efficacy and unwanted toxicity representation...
Jean Clairambault
.
A Step Toward Optimization of Cancer Therapeutics [Chronobiological In...
References
(31)
A Serum Shock Induces Circadian Gene Expression in Mammalian Tissue Culture Cells
(
Citations: 536
)
Aurélio Balsalobre
,
Francesca Damiola
,
Ueli Schibler
Journal:
Cell
, vol. 93, no. 6, pp. 929-937, 1998
Molecular Bases for Circadian Clocks
(
Citations: 963
)
Jay C Dunlap
Journal:
Cell
, vol. 96, no. 2, pp. 271-290, 1999
Interacting molecular loops in the mammalian circadian clock
(
Citations: 235
)
L. P. Shearman
,
S. Sriram
,
D. R. Weaver
Journal:
Science
, 2000
Positional Cloning of the Mouse Circadian Clock Gene
(
Citations: 476
)
David P King
,
Yaliang Zhao
,
Ashvin M Sangoram
,
Lisa D Wilsbacher
,
Minoru Tanaka
,
Marina P Antoch
,
Thomas D. L Steeves
,
Martha Hotz Vitaterna
,
Jon M Kornhauser
,
Phillip L Lowrey
,
Fred W Turek
,
Joseph S Takahashi
Journal:
Cell
, vol. 89, no. 4, pp. 641-653, 1997
Diurnal cortisol rhythm as a predictor of breast cancer survival
(
Citations: 196
)
S. E. Sephaton
,
R. M. Sapolsky
,
H. C. Kraemer
,
D. Spiegel
Published in 2000.
Sort by:
Citations
(39)
Temporal profiles of physical activity and energy expenditure in cancer in-patients
Saba Taj
,
Vivek Choudhary
,
Arti Parganiha
Journal:
Biological Rhythm Research - BIOL RHYTHM RES
, vol. ahead-of-p, no. ahead-of-p, pp. 1-17, 2012
Circadian rhythm and cell population growth
(
Citations: 1
)
Jean Clairambault
,
Stéphane Gaubert
,
Thomas Lepoutre
Journal:
Mathematical and Computer Modelling - MATH COMPUT MODELLING
, vol. 53, no. 7-8, pp. 1558-1567, 2011
Chronotherapy and the molecular clock: Clinical implications in oncology
(
Citations: 3
)
Pasquale F. Innominato
,
Francis A. Lévi
,
Georg A. Bjarnason
Journal:
Advanced Drug Delivery Reviews - ADVAN DRUG DELIVERY REV
, vol. 62, no. 9, pp. 979-1001, 2010
Chronopharmaceutics: Pharmaceutics Focused on Biological Rhythm
(
Citations: 5
)
Shigehiro Ohdo
Journal:
Biological & Pharmaceutical Bulletin - BIOL PHARM BULL
, vol. 33, no. 2, pp. 159-167, 2010
Diurnal cortisol dysregulation, functional disability, and depression in women with ovarian cancer
Aliza Z. Weinrib
,
Sandra E. Sephton
,
Koen DeGeest
,
Frank Penedo
,
David Bender
,
Bridget Zimmerman
,
Clemens Kirschbaum
,
Anil K. Sood
,
David M. Lubaroff
,
Susan K. Lutgendorf
Journal:
Cancer
, 2010