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Timing of Antibiotic Administration and Outcomes for Medicare Patients Hospitalized With Community-Acquired Pneumonia

Timing of Antibiotic Administration and Outcomes for Medicare Patients Hospitalized With Community-Acquired Pneumonia,Peter M. Houck,Dale W. Bratzler,

Timing of Antibiotic Administration and Outcomes for Medicare Patients Hospitalized With Community-Acquired Pneumonia   (Citations: 161)
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sion (11.6% vs 12.7%; AOR, 0.85; 95% CI, 0.76-0.95), and LOS exceeding the 5-day median (42.1% vs 45.1%; AOR, 0.90; 95% CI, 0.83-0.96). Mean LOS was 0.4 days shorterwithantibioticadministrationwithin4hoursthan withlateradministration.Timingwasnotassociatedwith readmission.Antibioticadministrationwithin4hoursof arrival was documented for 60.9% of all patients and for more than 50% of patients regardless of hospital char- acteristics.
Published in 2004.
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    • ...Houck et al. also reported in a retrospective analysis of 13,711 hospitalized Medicare patients with CAP that antibiotic therapy within 4 hours of presentation was associated with a lower in-hospital and 30-day mortality than later treatment (6.8% versus 7.4%, respectively, p= 0.005; and 11.6% versus 12.7%, respectively; p=0.03) [7]...
    • ...Second, we have included patients with confirmed diagnosis of pneumonia unlike the previous two studies where they included patients with a working diagnosis of pneumonia [6, 7]. Third, our study included high risk patients where the majority of patients had chronic comorbid conditions and had a PSI Class≥3...

    M. S. Baderet al. Antibiotic administration longer than eight hours after triage and mor...

    • ...To compare the results of the statistical models developed from Medicare claims with those from models using data collected from medical records, we identified a sample of patients for whom we had both administrative claims and detailed chart abstracted medical record data. The medical record data were obtained from the CMS National Pneumonia Project, in which patient charts from hospitalizations for pneumonia are routinely abstracted ...

    Dale W. Bratzleret al. An Administrative Claims Model for Profiling Hospital 30Day Mortality ...

    • ...Previous studies demonstrating the importance of appropriateness from AT usually used larger cohorts of patients [1,2,5,35] or analyzed selected populations with a single disease [3,4,35,36]...
    • ...Previous studies demonstrating the importance of appropriateness from AT usually used larger cohorts of patients [1,2,5,35] or analyzed selected populations with a single disease [3,4,35,36]...

    Philippe Montraverset al. Strategies of initiation and streamlining of antibiotic therapy in 41 ...

    • ...In the treatment of community-acquired pneumonia (CAP), several initial processes of care have been associated with improved survival, including the timely delivery and appropriate selection of antibiotic therapy, and acquisition of blood cultures prior to initiating antibiotic therapy [8-11]...

    Christopher R Freiet al. Disparities of Care for African-Americans and Caucasians with Communit...

    • ...The first 4 to 6 h in the treatment of these patients are of crucial importance to decrease not only the morbidity and mortality [1–5], but also other outcomes like the duration of hospital stay [2, 5, 6]. Recognition of prognostic factors in an early stage of the treatment will influence further treatment...

    Charlotte F. J. van Tuijnet al. Prognostic factors for important clinical outcomes in patients with a ...

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