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SWCNT PEG-eggs: Single-walled carbon nanotubes in biocompatible shell-crosslinked micelles

SWCNT PEG-eggs: Single-walled carbon nanotubes in biocompatible shell-crosslinked micelles,10.1016/j.carbon.2007.07.006,Carbon,Runtang Wang,Paul Cheru

SWCNT PEG-eggs: Single-walled carbon nanotubes in biocompatible shell-crosslinked micelles   (Citations: 2)
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Pristine, individualized single-walled carbon nanotubes (SWCNTs) have been noncovalently captured within PEG-terminated block copolymer amphiphiles. Two cross-linkable amphiphiles were evaluated: polyethylene glycol-polyacrylic acid-polystyrene (PEG-PAA-PS) and polyethylene glycol-polybutadiene (PEG-PB). The resulting self-assembled PEG-PAA-PS structures, called PEG-eggs, are freely soluble in water and stable in physiological media. SWCNTs in PEG-eggs retain their intrinsic near-infrared fluorescence, resist exchange with serum proteins, and are non-cytotoxic to mouse macrophage and human renal cells based on in vitro viability assays.
Journal: Carbon , vol. 45, no. 12, pp. 2388-2393, 2007
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    • ...PEG is a well-established, benign bio-passivating material [10]...
    • ...Previous publications showed that non-covalently functionalized SWNTs with PEG have a higher resistance to systemic clearance than that without PEG functionalization, because the sheath of PEG can prevent clearance of SWNTs by the reticuloendothelial system and can prolong their persistence in blood and humor circulation [10, 27]...

    Zhongmin Ouet al. Functional single-walled carbon nanotubes based on an integrin alphavb...

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