Tissue-Specific Expression of a Drosophila Calcium-Activated Potassium Channel
The Drosophila slowpoke (s/o) gene encodes a subunit of a CAK channel homologous to the vertebrate BK channel. We have examined s/o expression throughout develop- ment. It is expressed in muscle cells, neurons of the CNS and PNS, mushroom bodies, a limited number of cells in embryonic and larval midgut and in epithelial-derived tra- cheal cells. The promoter has been cloned and shown to direct expression in the same pattern as the endogenous gene in both neural and epithelial-derived cells. During pu- pariation and embryogenesis, s/o is expressed in muscles many hours prior to the appearance of functional channels.
Published in 1995.