Top publications in molecular biology 401–500 of 367,163 results
Publications Citations  
401
Meta-analysis of whole-genome linkage scans of bipolar disorder and schizophrenia (2002) 418
402
Shelterin: the protein complex that shapes and safeguards human telomeres (2005) 418
403
Nonsense-mediated mRNA decayin health and disease (1999) 417
404
Expression of achaete-scute homolog 3 in Xenopus embryos converts ectodermal cells to a neural fate (1994) 416
405
Scansite 2.0: proteome-wide prediction of cell signaling interactions using short sequence motifs (2003) 416
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Genomic DNA methylation: the mark and its mediators (2006) 416
407
miRNPs: a novel class of ribonucleoproteins containing numerous microRNAs (2002) 415
408
Distribution and cloning of eukaryotic mRNAs by means of differential display: refinements and optimization (1993) 415
409
An Integrated Stress Response Regulates Amino Acid Metabolism and Resistance to Oxidative Stress (2003) 415
410
MAPPFinder: using Gene Ontology and GenMAPP to create a global gene-expression profile from microarray data (2003) 414
411
The length and location of CAG trinucleotide repeats in the androgen receptor N-terminal domain affect transactivation function (1994) 414
412
Simple sequences are ubiquitous repetitive components of eukaryotic genomes (1984) 413
413
In vitro propagation and transcriptional profiling of human mammary stem/progenitor cells (2003) 412
414
The economics of ribosome biosynthesis in yeast (1999) 411
415
The p21Cip1 and p27Kip1 CDK `inhibitors' are essential activators of cyclin D-dependent kinases in murine fibroblasts (1999) 411
416
The dynamin superfamily: universal membrane tubulation and fission molecules? (2004) 410
417
Recognition of the polyubiquitin proteolytic signal (2000) 409
418
Oligoribonucleotide synthesis using T7 RNA polymerase and synthetic DNA templates (1987) 408
419
Disruption of two novel genes by a translocation co-segregating with schizophrenia (2000) 408
420
The GRID: The General Repository for Interaction Datasets (2003) 408
421
Database resources of the National Center for Biotechnology Information (2006) 407
422
The PROSITE database, its status in 1997 (1997) 407
423
Fluidity parameters of lipid regions determined by fluorescence polarization (1978) 407
424
KEGG: Kyoto Encyclopedia of Genes and Genomes (1999) 407
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Evaluation of 2′,7′-Dichlorofluorescin and Dihydrorhodamine 123 as Fluorescent Probes for Intracellular H2O2 in Cultured Endothelial Cells (1993) 406
426
Transcription regulation by histone methylation: interplay between different covalent modifications of the core histone tails (2001) 406
427
Force and focal adhesion assembly: a close relationship studied using elastic micropatterned substrates (2001) 406
428
Fatty acylation of proteins: new insights into membrane targeting of myristoylated and palmitoylated proteins (1999) 405
429
Valproic acid defines a novel class of HDAC inhibitors inducing differentiation of transformed cells (2001) 405
430
Nonsense-mediated mRNA decay: splicing, translation and mRNP dynamics (2004) 403
431
A requirement for bone morphogenetic protein-7 during development of the mammalian kidney and eye (1995) 402
432
Pre-mRNA splicing and human disease (2003) 402
433
The Evolution of Transcriptional Regulation in Eukaryotes (2003) 402
434
BID: a novel BH3 domain-only death agonist (1996) 401
435
Interaction of the Fanconi Anemia Proteins and BRCA1 in a Common Pathway (2001) 401
436
ERM proteins and merlin: integrators at the cell cortex (2002) 399
437
A biochemical framework for RNA silencing in plants (2003) 398
438
The ubiquitin-proteasome pathway: on protein death and cell life (1998) 397
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GenBank (2006) 394
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Caveolar endocytosis of simian virus 40 reveals a new two-step vesicular-transport pathway to the ER (2001) 394
441
NCBI GEO: mining millions of expression profiles - database and tools (2005) 393
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Mice lacking progesterone receptor exhibit pleiotropic reproductive abnormalities (1995) 393
443
The RDP (Ribosomal Database Project) (1997) 392
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Microbial gene identification using interpolated Markov models (1998) 392
445
RANK is essential for osteoclast and lymph node development (1999) 392
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The glamour and gloom of glycogen synthase kinase-3 (2004) 392
447
Recent improvements to the SMART domain-based sequence annotation resource (2002) 391
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Glutathione Transferases—Structure and Catalytic Activit (1988) 391
449
Evaluation of Multidimensional Chromatography Coupled with Tandem Mass Spectrometry (LC/LC−MS/MS) for Large-Scale Protein Analysis:  The Yeast Proteome (2003) 391
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Soluble protein oligomers in neurodegeneration: lessons from the Alzheimer's amyloid β-peptide (2007) 391
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The measurement and mechanism of lipid peroxidation in biological systems (1990) 390
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‘DNA Strider’: a ‘C’ program for the fast analysis of DNA and protein sequences on the Apple Macintosh family of computers (1988) 390
453
The general transcription factors of RNA polymerase II (1996) 390
454
Deletion screening of the Duchenne muscular dystrophy locus via multiplex DNA amplification (1988) 389
455
Evolutionary conservation in the untranslated regions of actin mRNAs: DNA sequence of a human beta-actin cDNA (1984) 389
456
Codon usage in bacteria: correlation with gene expressivity (1982) 389
457
Molecular cloning and functional analysis of the adenovirus E1A-associated 300-kD protein (p300) reveals a protein with properties of a transcriptional adaptor (1994) 388
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Lethal skeletal dysplasia from targeted disruption of the parathyroid hormone-related peptide gene (1994) 388
459
Terminal Differentiation of Human Breast Cancer through PPARγ (1998) 388
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PPARγ Mediates High-Fat Diet–Induced Adipocyte Hypertrophy and Insulin Resistance (1999) 388
461
Indian hedgehog signaling regulates proliferation and differentiation of chondrocytes and is essential for bone formation (1999) 387
462
E2F integrates cell cycle progression with DNA repair, replication, and G2/M checkpoints (2002) 387
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The diverse functions of histone lysine methylation (2005) 387
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Focal adhesion kinase: in command and control of cell motility (2005) 387
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A new efficient gene disruption cassette for repeated use in budding yeast (1996) 386
466
A homologue of Drosophila aurora kinase is oncogenic and amplified in human colorectal cancers (1998) 386
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Characterization of three RXR genes that mediate the action of 9-cis retinoic acid (1992) 386
468
HER2 (neu) Signaling Increases the Rate of Hypoxia-Inducible Factor 1  (HIF-1 ) Synthesis: Novel Mechanism for HIF-1-Mediated Vascular Endothelial Growth Factor Expression (2001) 386
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Alignment of whole genomes (1999) 384
470
Signaling through focal adhesion kinase (1999) 384
471
MUST, a computer package of Management Utilities for Sequences and Trees (1993) 383
472
Annexin V-affinity assay: a review on an apoptosis detection system based on phosphatidylserine exposure (1998) 383
473
Cyclin D1 is a nuclear protein required for cell cycle progression in G1 (1993) 382
474
Endothelial PAS domain protein 1 (EPAS1), a transcription factor selectively expressed in endothelial cells (1997) 382
475
MethyLight: a high-throughput assay to measure DNA methylation (2000) 382
476
Protein kinase C - a question of specificity (1994) 381
477
ErbB-2, the preferred heterodimerization partner of all ErbB receptors, is a mediator of lateral signaling (1997) 381
478
The PredictProtein server (2004) 380
479
Messenger-RNA-binding proteins and the messages they carry (2002) 380
480
Determination of DNA base composition by reversed-phase high-performance liquid chromatography (1984) 378
481
The Gene Ontology Annotation (GOA) Database: sharing knowledge in Uniprot with Gene Ontology (2004) 378
482
Alternative pre-mRNA splicing: the logic of combinatorial control (2000) 378
483
Biological Tyrosine Nitration: A Pathophysiological Function of Nitric Oxide and Reactive Oxygen Species (1998) 378
484
ArrayExpress - a public repository for microarray gene expression data at the EBI (2003) 377
485
Ubisemiquinone is the electron donor for superoxide formation by complex III of heart mitochondria*1 (1985) 377
486
Analysis of E.Coli Pormoter sequences (1987) 376
487
The MAP kinase cascade is essential for diverse signal transduction pathways (1993) 376
488
Versatile and open software for comparing large genomes (2004) 376
489
The spindle-assembly checkpoint in space and time (2007) 376
490
CD44: From adhesion molecules to signalling regulators (2003) 375
491
Binary Agrobacterium vectors for plant trans-formation (1984) 374
492
Annexins: the problem of assessing the biological role for a gene family of multifunctional calcium- and phospholipid-binding proteins (1994) 374
493
Oxygen sensing by HIF hydroxylases (2004) 374
494
The modification of mammalian membrane polyunsaturated fatty acid composition in relation to membrane fluidity and function (1984) 373
495
Compilation of tRNA sequences and sequences of tRNA genes (1998) 372
496
p53-dependent and independent expression of p21 during cell growth, differentiation, and DNA damage (1995) 372
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DNA damage activates p53 through a phosphorylation-acetylation cascade (1998) 372
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CDD: a conserved domain database for interactive domain family analysis (2007) 372
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A new nomenclature for the laminins (1994) 371
500
Essential contribution of caspase 3/CPP32 to apoptosis and its associated nuclear changes (1998) 370