Top publications in toxicology 1–100 of 152,523 results
Publications Citations  
1
PHARMACOLOGY AND FUNCTIONS OF METABOTROPIC GLUTAMATE RECEPTORS (1997) 1215
2
CYCLOOXYGENASES 1 AND 2 (1998) 934
3
THE HEME OXYGENASE SYSTEM:A Regulator of Second Messenger Gases (1997) 883
4
Polychlorinated Biphenyls (PCBs): Environmental Impact, Biochemical and Toxic Responses, and Implications for Risk Assessment (1994) 707
5
Polychlorinated biphenyls (PCBs), dibenzo-p-dioxins (PCDDs), dibenzofurans (PCDFs), and related compounds: Environmental and mechanistic considerations which support the development of toxic equivalency factors (TEFs) (1990) 678
6
The Excitatory Amino Acid Receptors: Their Classes, Pharmacology, and Distinct Properties in the Function of the Central Nervous System (1989) 653
7
BIOCHEMICAL, CELLULAR, AND PHARMACOLOGICAL ASPECTS OF THE MULTIDRUG TRANSPORTER1 (1999) 646
8
Fish bioaccumulation and biomarkers in environmental risk assessment: a review (2003) 646
9
Free radicals, metals and antioxidants in oxidative stress-induced cancer (2006) 636
10
Cognitive Deficit in 7YearOld Children with Prenatal Exposure to Methylmercury (1997) 624
11
GLUTATHIONE TRANSFERASES (2005) 616
12
Excitatory Amino Acid Transmitters (1981) 550
13
Evaluation of the probe 2',7'-dichlorofluorescin as an indicator of reactive oxygen species formation and oxidative stress (1992) 549
14
The ARYL Hydrocarbon Receptor Complex (1995) 538
15
Free Radicals as Mediators of Tissue Injury and Disease (1993) 498
16
Toxicity determined in vitro by morphological alterations and neutral red absorption (1985) 463
17
Occurrence, fate, and removal of pharmaceutical residues in the aquatic environment: a review of recent research data (2002) 461
18
Biosynthesis and Metabolism of Endothelium-Derived Nitric Oxide (1990) 451
19
2,3,7,8-Tetrachlorodibenzo-thorn-Dioxin and Related Halogenated Aromatic Hydrocarbons: Examination of the Mechanism of Toxicity (1982) 443
20
INDUCTION OF CYTOCHROME P4501A1 (1999) 429
21
Pulmonary Toxicity of Single-Wall Carbon Nanotubes in Mice 7 and 90 Days After Intratracheal Instillation (2003) 425
22
Oxidative Damage and Tyrosine Nitration from Peroxynitrite (1996) 415
23
The 2005 World Health Organization Reevaluation of Human and Mammalian Toxic Equivalency Factors for Dioxins and Dioxin-Like Compounds (2006) 409
24
Endocrine Disruption in Wildlife: A Critical Review of the Evidence (1998) 399
25
Ecotoxicology of Organotin Compounds (1996) 389
26
Neurotoxins that Act on Voltage-Sensitive Sodium Channels in Excitable Membranes (1980) 388
27
Role of human cytochrome P-450 IIE1 in the oxidation of many low molecular weight cancer suspects (1991) 374
28
14-3-3 Proteins: Structure, Function, and Regulation (2000) 373
29
Specific Pharmacology of Calcium in Myocardium, Cardiac Pacemakers, and Vascular Smooth Muscle (1977) 365
30
Peroxynitrite, a cloaked oxidant formed by nitric oxide and superoxide (1992) 365
31
METALLOTHIONEIN: An Intracellular Protein to Protect Against Cadmium Toxicity (1999) 365
32
Efficient Analysis of Experimental Observations (1980) 363
33
Comparative Pulmonary Toxicity Assessment of Single-wall Carbon Nanotubes in Rats (2003) 353
34
Translocation of Inhaled Ultrafine Particles to the Brain (2004) 351
35
Drug-like properties and the causes of poor solubility and poor permeability (2000) 348
36
New method for determining allowable daily intakes (1984) 341
37
THE ROLE OF OXIDATIVE STRESS IN CARCINOGENESIS (2004) 337
38
Oxidative Stress in Neurodegenerative Diseases (1996) 326
39
Amphetamine: Effects on Catecholamine Systems and Behavior (1993) 326
40
Oxidation of toxic and carcinogenic chemicals by human cytochrome P-450 enzymes (1991) 322
41
Minamata Disease: Methylmercury Poisoning in Japan Caused by Environmental Pollution (1995) 321
42
Evaluation of Chemicals with Endocrine Modulating Activity in a Yeast-Based Steroid Hormone Receptor Gene Transcription Assay (1997) 320
43
INHIBITION OF CARCINOGENESIS BY TEA (2002) 320
44
Human UDP-Glucuronosyltransferases: Metabolism, Expression, and Disease (2000) 319
45
The PAS Superfamily: Sensors of Environmental and Developmental Signals (2000) 317
46
ACTIVATION OF THE ARYL HYDROCARBON RECEPTOR BY STRUCTURALLY DIVERSE EXOGENOUS AND ENDOGENOUS CHEMICALS (2003) 316
47
Effect of Chlorpromazine or Haloperidol on Formation of 3-Methoxytyramine and Normetanephrine in Mouse Brain (2009) 315
48
Muscarinic Receptor Subtypes (1990) 311
49
Glutathione: Toxicological Implications (1990) 311
50
REGULATION OF GENE EXPRESSION BY REACTIVE OXYGEN (1999) 310
51
REGULATORY MECHANISMS CONTROLLING GENE EXPRESSION MEDIATED BY THE ANTIOXIDANT RESPONSE ELEMENT (2003) 306
52
Results of a two-year chronic toxicity and oncogenicity study of 2,3,7,8-tetrachlorodibenzo-p-dioxin in rats (1978) 300
53
PLEIOTROPIC EFFECTS OF STATINS (2005) 300
54
Role of Quinones in Toxicology † (2000) 297
55
Nicotinic Receptors at the Amino Acid Level (2000) 296
56
Superoxide Radical: An Endogenous Toxicant (1983) 295
57
Developmental and Reproductive Toxicity of Dioxins and Related Compounds: Cross-Species Comparisons (1993) 294
58
Pharmacology of Cloned P2X Receptors (2000) 293
59
The Human Hepatic Cytochromes P450 Involved in Drug Metabolism (1992) 292
60
Carcinogenesis by Hepatic Peroxisome Proliferators: Evaluation of the Risk of Hypolipidemic Drugs and Industrial Plasticizers to Humans (1983) 290
61
PROSTANOID RECEPTORS: Subtypes and Signaling 1 (2001) 289
62
Perinatal Exposure to the Phthalates DEHP, BBP, and DINP, but Not DEP, DMP, or DOTP, Alters Sexual Differentiation of the Male Rat (2000) 288
63
THE ROLE OF RECEPTOR KINASES AND ARRESTINS IN G PROTEIN-COUPLED RECEPTOR REGULATION (1998) 287
64
Recent Advances in Arsenic Carcinogenesis: Modes of Action, Animal Model Systems, and Methylated Arsenic Metabolites (2001) 284
65
Structure, Catalytic Mechanism, and Evolution of the Glutathione Transferases (1997) 283
66
Exposure to Carbon Nanotube Material: Assessment of Nanotube Cytotoxicity using Human Keratinocyte Cells (2003) 280
67
The Excitatory Amino Acid Receptors: Their Classes, Pharmacology, And Distinct Properties In The Function Of The Central Nervous System (1989) 279
68
Mechanisms of Hepatotoxicity (2002) 277
69
Health Effects of Endocrine-Disrupting Chemicals on Wildlife, with Special Reference to the European Situation (2000) 275
70
INTERACTIONS BETWEEN MONOAMINES, GLUTAMATE, AND GABA IN SCHIZOPHRENIA: New Evidence (2001) 273
71
Comparative toxicity of trivalent and pentavalent inorganic and methylated arsenicals in rat and human cells (2000) 272
72
CYTOCHROME P-450 3A4: Regulation and Role in Drug Metabolism (1999) 265
73
Review of Epidemiological Evidence of Health Effects of Particulate Air Pollution (1995) 262
74
IN VITRO AND IN VIVO DRUG INTERACTIONS INVOLVING HUMAN CYP3A (1998) 261
75
Potent competitive interactions of some brominated flame retardants and related compounds with human tranthyretin in vitro (2000) 260
76
Molecular and cellular mechanisms of cadmium carcinogenesis (2003) 259
77
Aryl-hydrocarbon Receptor-Deficient Mice Are Resistant to 2,3,7,8-Tetrachlorodibenzo- p-dioxin-Induced Toxicity (1996) 258
78
Perfluoroalkyl Acids: A Review of Monitoring and Toxicological Findings (2007) 258
79
MOLECULAR APPROACH TO ADENOSINE RECEPTORS: Receptor-Mediated Mechanisms of Tissue Protection (2001) 257
80
Calcium-Mediated Mechanisms in Chemically Induced Cell Death (1992) 255
81
Multidrug resistance proteins: role of P-glycoprotein, MRP1, MRP2, and BCRP (ABCG2) in tissue defense (2005) 255
82
ALZHEIMER'S DISEASE: Molecular Understanding Predicts Amyloid-Based Therapeutics (2003) 254
83
Pharmacology of Cannabinoid Receptors (1995) 250
84
Complexity and Diversity of Mammalian Adenylyl Cyclases (1996) 250
85
REGULATION AND INHIBITION OF PHOSPHOLIPASE A2 (1999) 250
86
Reactive Oxygen-Mediated Protein Oxidation in Aging and Disease (1997) 248
87
Stress Proteins in Aquatic Organisms: An Environmental Perspective (1993) 247
88
Administration of potentially antiandrogenic pesticides (procymidone, linuron, iprodione, chlozolinate, p,p′DDE, and ketoconazole) and toxic substances (dibutyl- and diethylhexyl phthalate, PCB 169, and ethane dimethane sulphonate) during sexual differentiation produces diverse profiles of reproductive malformations in the male rat (1999) 245
89
EXTRAPULMONARY TRANSLOCATION OF ULTRAFINE CARBON PARTICLES FOLLOWING WHOLE-BODY INHALATION EXPOSURE OF RATS (2002) 245
90
Cadmium, Gene Regulation, and Cellular Signalling in Mammalian Cells (1997) 241
91
The Plasticizer Diethylhexyl Phthalate Induces Malformations by Decreasing Fetal Testosterone Synthesis during Sexual Differentiation in the Male Rat (2000) 240
92
GLUTAMATERGIC MECHANISMS IN SCHIZOPHRENIA (2002) 240
93
Size-Dependent Proinflammatory Effects of Ultrafine Polystyrene Particles: A Role for Surface Area and Oxidative Stress in the Enhanced Activity of Ultrafines (2001) 238
94
The Role of Endothelium in the Responses of Vascular Smooth Muscle to Drugs (1984) 237
95
Cell Survival Responses to Environmental Stresses Via the Keap1-Nrf2ARE Pathway (2007) 237
96
Molecular Diversity of the Dopamine Receptors (1993) 235
97
In vitro toxicity of nanoparticles in BRL 3A rat liver cells (2005) 235
98
Effects of antioxidant enzymes in the molecular control of reactive oxygen species toxicology (2000) 232
99
PROPERTIES AND BIOLOGICAL ACTIVITIES OF THIOREDOXINS (2001) 232
100
CRF AND CRF RECEPTORS: Role in Stress Responsivity and Other Behaviors (2004) 232