Top publications in endocrinology 1–100 of 271,761 results
Publications Citations  
1
Intensive Blood-Glucose Control with Sulfonylureas or Insulin Compared with Conventional Treatment and Risk of Complications in Patients with Type 2 Diabetes (1999) 1837
2
Insulin-Like Growth Factors and Their Binding Proteins: Biological Actions (1995) 1771
3
The Biology of Vascular Endothelial Growth Factor (1997) 1760
4
Absolute quantification of mRNA using real-time reverse transcription polymerase chain reaction assays (2000) 1411
5
Quantitative analysis of dose-effect relationships: the combined effects of multiple drugs or enzyme inhibitors (1984) 1246
6
How Do Glucocorticoids Influence Stress Responses? Integrating Permissive, Suppressive, Stimulatory, and Preparative Actions (2000) 1205
7
Comparison of the Ligand Binding Specificity and Transcript Tissue Distribution of Estrogen Receptors   and (1997) 1089
8
Peroxisome Proliferator-Activated Receptors: Nuclear Control of Metabolism (1999) 999
9
Physiological Functions of Glucocorticoids in Stress and Their Relation to Pharmacological Actions (1984) 987
10
Hypoadiponectinemia in Obesity and Type 2 Diabetes: Close Association with Insulin Resistance and Hyperinsulinemia (2001) 979
11
Mitogen-Activated Protein (MAP) Kinase Pathways: Regulation and Physiological Functions (2001) 975
12
Graphical Evaluation of Blood-to-Brain Transfer Constants from Multiple-Time Uptake Data (1983) 913
13
Quantification of mRNA using real-time reverse transcription PCR (RT-PCR): trends and problems (2002) 776
14
Molecular basis of human hypertension: Role of angiotensinogen (1992) 772
15
Adipose Tissue as an Endocrine Organ (2000) 762
16
Adipose Tissue as an Endocrine Organ (2004) 757
17
A rapid and potent natriuretic response to intravenous injection of atrial myocardial extract in rats (1981) 754
18
Quantitative Insulin Sensitivity Check Index: A Simple, Accurate Method for Assessing Insulin Sensitivity In Humans (2000) 754
19
Coated Charcoal Immunoassay of Insulin (1965) 743
20
Two Receptor Systems for Corticosterone in Rat Brain: Microdistribution and Differential Occupation (1985) 743
21
Pineal Melatonin: Cell Biology of Its Synthesis and of Its Physiological Interactions (1991) 741
22
Vascular Endothelial Growth Factor: Basic Science and Clinical Progress (2004) 730
23
Interacting Appetite-Regulating Pathways in the Hypothalamic Regulation of Body Weight (1999) 726
24
Brain corticosteroid receptor balance in health and disease (1998) 722
25
Ghrelin Enhances Appetite and Increases Food Intake in Humans (2001) 721
26
A Critical Evaluation of Simple Methods for the Estimation of Free Testosterone in Serum (1999) 709
27
Modulation of Osteoclast Differentiation and Function by the New Members of the Tumor Necrosis Factor Receptor and Ligand Families (1999) 672
28
The Neuroendocrinology of Stress and Aging: The Glucocorticoid Cascade Hypothesis (1986) 670
29
Insulin Resistance and the Polycystic Ovary Syndrome: Mechanism and Implications for Pathogenesis (1997) 656
30
Environmentally persistent alkylphenolic compounds are estrogenic (1994) 651
31
Mediterranean Diet, Traditional Risk Factors, and the Rate of Cardiovascular Complications after 1 Myocardial Infarction. Final report of the Lyon Diet Heart Study (1999) 650
32
Organization of Ovine Corticotropin-Releasing Factor Immunoreactive Cells and Fibers in the Rat Brain: An Immunohistochemical Study (1983) 639
33
Nuclear Receptor Coregulators: Cellular and Molecular Biology (1999) 636
34
Estrogen Receptor Null Mice: What Have We Learned and Where Will They Lead Us? (1999) 630
35
Subcutaneous Adipose Tissue Releases Interleukin6, But Not Tumor Necrosis Factor , in Vivo (1997) 624
36
Subcutaneous and Visceral Adipose Tissue: Their Relation to the Metabolic Syndrome (2000) 608
37
Estrogen Actions in the Central Nervous System (1999) 602
38
CLINICAL ASSESSMENT OF BODY HAIR GROWTH IN WOMEN (1961) 588
39
The Novel Hypothalamic Peptide Ghrelin Stimulates Food Intake and Growth Hormone Secretion (2000) 579
40
Differential expression of peroxisome proliferator-activated receptors (PPARs): tissue distribution of PPAR-alpha, -beta, and -gamma in the adult rat (1996) 569
41
Insulin-Like Growth Factors I and II. Peptide, Messenger Ribonucleic Acid and Gene Structures, Serum, and Tissue Concentrations (1989) 545
42
The Role of the Hippocampus in Feedback Regulation of the Hypothalamic-Pituitary-Adrenocortical Axis (1991) 540
43
Steroid Receptor Interactions with Heat Shock Protein and Immunophilin Chaperones (1997) 538
44
THE SPECTRUM OF THYROID DISEASE IN A COMMUNITY: THE WHICKHAM SURVEY (1977) 535
45
Adiponectin and Adiponectin Receptors (2005) 522
46
Nutritional Regulation of the Insulin-Like Growth Factors (1994) 520
47
Molecular and Biological Properties of the Vascular Endothelial Growth Factor Family of Proteins (1992) 518
48
Bisphenol-A: an estrogenic substance is released from polycarbonate flasks during autoclaving (1993) 512
49
Aromatase deficiency in male and female siblings caused by a novel mutation and the physiological role of estrogens (1995) 512
50
The role of corticotropin-releasing factor in depression and anxiety disorders (1999) 512
51
The Vascular Endothelial Growth Factor Family: Identification of a Fourth Molecular Species and Characterization of Alternative Splicing of RNA (1991) 510
52
Ghrelin, a Novel Growth Hormone-Releasing Acylated Peptide, Is Synthesized in a Distinct Endocrine Cell Type in the Gastrointestinal Tracts of Rats and Humans (2000) 502
53
Relation of Body Fat Distribution to Metabolic Complications of Obesity (1982) 499
54
'Metabonomics': understanding the metabolic responses of living systems to pathophysiological stimuli via multivariate statistical analysis of biological NMR spectroscopic data (1999) 484
55
Simultaneous single isotope radioenzymatic assay of plasma norepinephrine, epinephrine and dopamine (1977) 480
56
Functional Connectivity: The Principal-Component Analysis of Large (PET) Data Sets (1993) 480
57
Purification, Characterization, and in vitro Differentiation of Cytotrophoblasts from Human Term Placentae (1986) 473
58
Low cerebrospinal fluid 5-hydroxyindoleacetic acid concentration differentiates impulsive from nonimpulsive violent behavior (1983) 472
59
Somatostatin and Its Receptor Family (1999) 472
60
NEUROPEPTIDE Y AND HUMAN PANCREATIC POLYPEPTIDE STIMULATE FEEDING BEHAVIOR IN RATS (1984) 464
61
Birth and Death of Bone Cells: Basic Regulatory Mechanisms and Implications for the Pathogenesis and Treatment of Osteoporosis (2000) 463
62
APPLICATION OF A RADIOIMMUNOASSAY FOR ANGIOTENSIN I TO THE PHYSIOLOGIC MEASUREMENTS OF PLASMA RENIN ACTIVITY IN NORMAL HUMAN SUBJECTS (1969) 461
63
Identity of Osteoclastogenesis Inhibitory Factor (OCIF) and Osteoprotegerin (OPG): A Mechanism by which OPG/OCIF Inhibits Osteoclastogenesis in Vitro (1998) 460
64
Vitamin D Deficiency and Secondary Hyperparathyroidism in the Elderly: Consequences for Bone Loss and Fractures and Therapeutic Implications (2001) 458
65
Prevalence and Predictors of Risk for Type 2 Diabetes Mellitus and Impaired Glucose Tolerance in Polycystic Ovary Syndrome: A Prospective, Controlled Study in 254 Affected Women (1999) 458
66
Structural Characterization and Biological Functions of Fibroblast Growth Factor (1987) 457
67
Critical Years and Stages of Puberty for Spinal and Femoral Bone Mass Accumulation during Adolescence (1991) 445
68
Leptin is a metabolic signal to the reproductive system (1996) 440
69
Leptin enters the brain by a saturable system independent of insulin (1996) 438
70
Prevalence of the Polycystic Ovary Syndrome in Unselected Black and White Women of the Southeastern United States: A Prospective Study (1998) 437
71
Prolactin (PRL) and Its Receptor: Actions, Signal Transduction Pathways and Phenotypes Observed in PRL Receptor Knockout Mice (1998) 436
72
Reactive Oxygen Radicals in Signaling and Damage in the Ischemic Brain (2001) 435
73
Serum TSH, T4, and Thyroid Antibodies in the United States Population (1988 to 1994): National Health and Nutrition Examination Survey (NHANES III) (2002) 427
74
The incidence of thyroid disorders in the community: a twenty-year follow-up of the Whickham Survey (1995) 426
75
Cellular Actions of the Insulin-Like Growth Factor Binding Proteins (2002) 423
76
Age Changes and Sex Differences in Serum Dehydroepiandrosterone Sulfate Concentrations throughout Adulthood (1984) 422
77
The Pineal and Its Hormones in the Control of Reproduction in Mammals (1980) 420
78
Use of cryoprotectant to maintain long-term peptide immunoreactivity and tissue morphology (1986) 419
79
Immune-Neuro-Endocrine Interactions: Facts and Hypotheses (1996) 416
80
Oxidative Stress and Stress-Activated Signaling Pathways: A Unifying Hypothesis of Type 2 Diabetes (2002) 415
81
Aromatase Cytochrome P450, The Enzyme Responsible for Estrogen Biosynthesis (1994) 414
82
Antidepressants and Hypothalamic-Pituitary-Adrenocortical Regulation (1996) 413
83
Human Estrogen Receptor  Gene Structure, Chromosomal Localization, and Expression Pattern (1997) 410
84
Sex Steroids and the Construction and Conservation of the Adult Skeleton (2002) 409
85
Influence of Season and Latitude on the Cutaneous Synthesis of Vitamin D3: Exposure to Winter Sunlight in Boston and Edmonton Will Not Promote Vitamin D3 Synthesis in Human Skin (1988) 405
86
Graphical Analysis of Reversible Radioligand Binding from Time-Activity Measurements Applied to [N-11C-methyl]-(-)Cocaine PET Studies in Human Subjects (1990) 402
87
Plasma Ghrelin Levels in Lean and Obese Humans and the Effect of Glucose on Ghrelin Secretion (2002) 402
88
Measurement of dimeric inhibin B throughout the human menstrual cycle (1996) 401
89
Localization of the melanocortin-4 receptor (MC4-R) in neuroendocrine and autonomic control circuits in the brain (1994) 398
90
Stomach Is a Major Source of Circulating Ghrelin, and Feeding State Determines Plasma Ghrelin-Like Immunoreactivity Levels in Humans (2001) 396
91
Uncovering Molecular Mechanisms Involved in Activation of G Protein-Coupled Receptors (2000) 396
92
Androgen Receptor Defects: Historical, Clinical, and Molecular Perspectives (1995) 394
93
The Tissue Distribution of the mRNA of Ghrelin and Subtypes of Its Receptor, GHS-R, in Humans (2002) 394
94
Cell Membrane and Nuclear Estrogen Receptors (ERs) Originate from a Single Transcript: Studies of ER  and ER  Expressed in Chinese Hamster Ovary Cells (1999) 392
95
Interaction of Estrogenic Chemicals and Phytoestrogens with Estrogen Receptor (1998) 391
96
Omental and Subcutaneous Adipose Tissues of Obese Subjects Release Interleukin6: Depot Difference and Regulation by Glucocorticoid (1998) 387
97
Fatty Acids, Eicosanoids, and Hypolipidemic Agents Identified as Ligands of Peroxisome Proliferator-Activated Receptors by Coactivator-Dependent Receptor Ligand Assay (1997) 387
98
Biological Roles of Fibroblast Growth Factor2 (1997) 385
99
Inflammatory Mediators and Stroke: New Opportunities for Novel Therapeutics (1999) 385
100
Assessment of Insulin Sensitivity in Vivo (1985) 384