RSS for Geoffrey M. Downshttp://academic.research.microsoft.com/Rss.aspx?id=3436824Search RSS feed for Microsoft Academic SearchMSRA Libra RSS Burner(c)2008 Microsoft Corpration, All right reserved.Sat, 18 May 2013 10:25:17 GMTSat, 18 May 2013 10:25:17 GMTGeoffrey M. Downs (Personal Info) http://academic.research.microsoft.com/Author/3436824Sat, 18 May 2013 10:25:17 GMT

Publications: 40

Citation Count: 670

G-index: 25

Field Rating: 11

Fields of study: Computational Chemistry, Applied Chemistry, Biochemistry

Homepage:

Permanent Link: http://academic.research.microsoft.com/Author/3436824

]]>34375341125Use of Markush structure analysis techniques for descriptor generation and clustering of large combinatorial librarieshttp://academic.research.microsoft.com/Publication/49534035Sat, 18 May 2013 10:25:17 GMT343682449534035John M Barnard, Geoff M Downs, Annette von Scholley-Pfab, Robert D Brown

Peptides, vol. 18, no. 4, pp. 452-463, 2000

]]>Chemical Similarity Searchinghttp://academic.research.microsoft.com/Publication/829721Sat, 18 May 2013 10:25:16 GMT3436824829721Peter Willett, John M. Barnard, Geoffrey M. Downs

J CHEM INF MODEL, vol. 38, no. 6, pp. 983-996, 1998

(Citations:313)

]]>Chemical Fragment Generation and Clustering Softwarehttp://academic.research.microsoft.com/Publication/830218Sat, 18 May 2013 10:25:15 GMT3436824830218John M. Barnard, Geoffrey M. Downs

J CHEM INF MODEL, vol. 37, no. 1, pp. 141-142, 1997

(Citations:21)

]]>Techniques for Generating Descriptive Fingerprints in Combinatorial Librarieshttp://academic.research.microsoft.com/Publication/830843Sat, 18 May 2013 10:25:14 GMT3436824830843Geoffrey M. Downs, John M. Barnard

J CHEM INF MODEL, vol. 37, no. 1, pp. 59-61, 1997

(Citations:21)

]]>Automated Descriptor Selection and Hyperstructure Generation to Assist SAR Studieshttp://academic.research.microsoft.com/Publication/24275525Sat, 18 May 2013 10:25:13 GMT343682424275525G. M. Downs, G. S. Gill, P. Willett, P. Walsh

SAR QSAR ENVIRON RES, vol. 3, no. 4, pp. 253-264, 1995

(Citations:1)

]]>Similarity Searching and Clustering of Chemical-Structure Databases Using Molecular Property Datahttp://academic.research.microsoft.com/Publication/830730Sat, 18 May 2013 10:25:12 GMT3436824830730Geoffrey M. Downs, Peter Willett, William Fisanick

JCISD, vol. 34, no. 5, pp. 1094-1102, 1994

(Citations:61)

]]>Hyperstructure model for chemical structure handling: Techniques for substructure searchinghttp://academic.research.microsoft.com/Publication/830979Sat, 18 May 2013 10:25:11 GMT3436824830979Robert D. Brown, Geoffrey M. Downs, Gareth Jones, Peter Willett

JCISD, vol. 34, no. 1, pp. 47-53, 1994

(Citations:2)

]]>Evaluation of the screening stages of the Sheffield Research Project on Computer Storage and Retrieval of Generic Chemical Structures in Patentshttp://academic.research.microsoft.com/Publication/829707Sat, 18 May 2013 10:25:10 GMT3436824829707John D. Holliday, Geoffrey M. Downs, Valerie J. Gillet, Michael F. Lynch, Winfried Dethlefsen

JCISD, vol. 34, no. 1, pp. 39-46, 1994

(Citations:1)

]]>Similarity Searching and Clustering of Chemical-Structure Databases Using Molecular Property Datahttp://academic.research.microsoft.com/Publication/23985656Sat, 18 May 2013 10:25:09 GMT343682423985656Geoffrey M. Downs, Peter Willett, William Fisanick

J CHEM INF MODEL, vol. 34, no. 5, pp. 1094-1102, 1994

(Citations:3)

]]>Hyperstructure model for chemical structure handling: Techniques for substructure searchinghttp://academic.research.microsoft.com/Publication/23985511Sat, 18 May 2013 10:25:08 GMT343682423985511Robert D. Brown, Geoffrey M. Downs, Gareth Jones, Peter Willett

J CHEM INF MODEL, vol. 34, no. 1, pp. 47-53, 1994

]]>Evaluation of the screening stages of the Sheffield Research Project on Computer Storage and Retrieval of Generic Chemical Structures in Patentshttp://academic.research.microsoft.com/Publication/23985510Sat, 18 May 2013 10:25:07 GMT343682423985510J. D. Holliday, G. M. Downs, V. J. Gillet, M. F. Lynch, Winfried Dethlefsen

J CHEM INF MODEL, vol. 34, no. 1, pp. 39-46, 1994

]]>Computer storage and retrieval of generic chemical structures in patents. 15. Generation of topological fragment descriptors from nontopological representations of generic structure componentshttp://academic.research.microsoft.com/Publication/829282Sat, 18 May 2013 10:25:06 GMT3436824829282John D. Holliday, Geoffrey M. Downs, Valerie J. Gillet, Michael F. Lynch

JCISD, vol. 33, no. 3, pp. 369-377, 1993

(Citations:6)

]]>Computer storage and retrieval of generic chemical structures in patents. 15. Generation of topological fragment descriptors from nontopological representations of generic structure componentshttp://academic.research.microsoft.com/Publication/23985395Sat, 18 May 2013 10:25:05 GMT343682423985395J. D. Holliday, G. M. Downs, V. J. Gillet, M. F. Lynch

J CHEM INF MODEL, vol. 33, no. 3, pp. 369-377, 1993

]]>Clustering of chemical structures on the basis of two-dimensional similarity measureshttp://academic.research.microsoft.com/Publication/830217Sat, 18 May 2013 10:25:04 GMT3436824830217John M. Barnard, Geoffrey M. Downs

JCISD, vol. 32, no. 6, pp. 644-649, 1992

(Citations:60)

]]>Computer storage and retrieval of generic chemical structures in patents. 14. Fragment generation from generic structureshttp://academic.research.microsoft.com/Publication/829281Sat, 18 May 2013 10:25:03 GMT3436824829281John D. Holliday, Geoffrey M. Downs, Valerie J. Gillet, Michael F. Lynch

JCISD, vol. 32, no. 5, pp. 453-462, 1992

(Citations:5)

]]>Hyperstructure model for chemical structure handling: generation and atom-by-atom searching of hyperstructureshttp://academic.research.microsoft.com/Publication/830987Sat, 18 May 2013 10:25:02 GMT3436824830987Robert D. Brown, Geoffrey M. Downs, Peter Willett, Anthony P. F. Cook

JCISD, vol. 32, no. 5, pp. 522-531, 1992

(Citations:3)

]]>Clustering of chemical structures on the basis of two-dimensional similarity measureshttp://academic.research.microsoft.com/Publication/23985319Sat, 18 May 2013 10:25:01 GMT343682423985319J. M. Barnard, G. M. Downs

J CHEM INF MODEL, vol. 32, no. 6, pp. 644-649, 1992

(Citations:3)

]]>Hyperstructure model for chemical structure handling: generation and atom-by-atom searching of hyperstructureshttp://academic.research.microsoft.com/Publication/23985296Sat, 18 May 2013 10:25:00 GMT343682423985296Robert D. Brown, Geoffrey M. Downs, Peter Willett, A. P. F. Cook

J CHEM INF MODEL, vol. 32, no. 5, pp. 522-531, 1992

(Citations:1)

]]>Computer storage and retrieval of generic chemical structures in patents. 14. Fragment generation from generic structureshttp://academic.research.microsoft.com/Publication/23985286Sat, 18 May 2013 10:24:59 GMT343682423985286J. D. Holliday, G. M. Downs, V. J. Gillet, M. F. Lynch

J CHEM INF MODEL, vol. 32, no. 5, pp. 453-462, 1992

]]>Computer storage and retrieval of generic chemical structures in patents. 13. Reduced graph generationhttp://academic.research.microsoft.com/Publication/829869Sat, 18 May 2013 10:24:58 GMT3436824829869Valerie J. Gillet, Geoffrey M. Downs, John D. Holliday, Michael F. Lynch, Winfried Dethlefsen

JCISD, vol. 31, no. 2, pp. 260-270, 1991

(Citations:18)

]]>Computer storage and retrieval of generic chemical structures in patents. 12. Principles of search operations involving parameter lists: matching-relations, user-defined match levels, and transition from the reduced graph search to the refined searchhttp://academic.research.microsoft.com/Publication/829312Sat, 18 May 2013 10:24:57 GMT3436824829312Winfried Dethlefsen, Michael F. Lynch, Valerie J. Gillet, Geoffrey M. Downs, John D. Holliday, John M. Barnard

JCISD, vol. 31, no. 2, pp. 253-260, 1991

(Citations:7)

]]>Computer Storage and Retrieval of Generic Chemical Structures in Patents. Part 12. Principles of Search Operations Involving Parameter Lists: Matching-Relations, User-Defined Match Levels, and Transition from the Reduced Graph Search to the Refined Searchhttp://academic.research.microsoft.com/Publication/45993492Sat, 18 May 2013 10:24:56 GMT343682445993492W. DETHLEFSEN, M. F. LYNCH, V. J. GILLET, G. M. DOWNS, J. D. HOLLIDAY, J. M. BARNARD

Cheminform, vol. 22, no. 34, pp. 266-266, 1991

(Citations:1)

]]>Computer storage and retrieval of generic chemical structures in patents. 13. Reduced graph generationhttp://academic.research.microsoft.com/Publication/23985142Sat, 18 May 2013 10:24:55 GMT343682423985142Valerie J. Gillet, Geoffrey M. Downs, John D. Holliday, Michael F. Lynch, Winfried Dethlefsen

J CHEM INF MODEL, vol. 31, no. 2, pp. 260-270, 1991

(Citations:1)

]]>Computer storage and retrieval of generic chemical structures in patents. 11. Theoretical aspects of the use of structure languages in a retrieval systemhttp://academic.research.microsoft.com/Publication/4396782Sat, 18 May 2013 10:24:54 GMT34368244396782Winfried Dethlefsen, Michael F. Lynch, Valerie J. Gillet, Geoffrey M. Downs, John D. Holliday, John M. Barnard

JCISD, vol. 31, no. 2, pp. 233-253, 1991

]]>Computer storage and retrieval of generic chemical structures in patents. 11. Theoretical aspects of the use of structure languages in a retrieval systemhttp://academic.research.microsoft.com/Publication/23985140Sat, 18 May 2013 10:24:53 GMT343682423985140Winfried Dethlefsen, Michael F. Lynch, Valerie J. Gillet, Geoffrey M. Downs, John D. Holliday, John M. Barnard

J CHEM INF MODEL, vol. 31, no. 2, pp. 233-253, 1991

]]>Computer storage and retrieval of generic chemical structures in patents. 12. Principles of search operations involving parameter lists: matching-relations, user-defined match levels, and transition from the reduced graph search to the refined searchhttp://academic.research.microsoft.com/Publication/23985141Sat, 18 May 2013 10:24:52 GMT343682423985141Winfried Dethlefsen, Michael F. Lynch, Valerie J. Gillet, Geoffrey M. Downs, John D. Holliday, John M. Barnard

J CHEM INF MODEL, vol. 31, no. 2, pp. 253-260, 1991

]]>Review of ring perception algorithms for chemical graphshttp://academic.research.microsoft.com/Publication/829150Sat, 18 May 2013 10:24:51 GMT3436824829150Geoffrey M. Downs, Valerie J. Gillet, John D. Holliday, Michael F. Lynch

JCISD, vol. 29, no. 3, pp. 172-187, 1989

(Citations:47)

]]>Computer storage and retrieval of generic chemical structures in patents. 9. An algorithm to find the extended set of smallest rings in structurally explicit genericshttp://academic.research.microsoft.com/Publication/828388Sat, 18 May 2013 10:24:50 GMT3436824828388Geoffrey M. Downs, Valerie J. Gillet, John D. Holliday, Michael F. Lynch

JCISD, vol. 29, no. 3, pp. 207-214, 1989

(Citations:19)

]]>Theoretical aspects of ring perception and development of the extended set of smallest rings concepthttp://academic.research.microsoft.com/Publication/828387Sat, 18 May 2013 10:24:49 GMT3436824828387Geoffrey M. Downs, Valerie J. Gillet, John D. Holliday, Michael F. Lynch

JCISD, vol. 29, no. 3, pp. 187-206, 1989

(Citations:13)

]]>Computer storage and retrieval of generic chemical structures in patents. 10. Assignment and logical bubble-up of ring screens for structurally explicit genericshttp://academic.research.microsoft.com/Publication/4396785Sat, 18 May 2013 10:24:48 GMT34368244396785Geoffrey M. Downs, Valerie J. Gillet, John D. Holliday, Michael F. Lynch

JCISD, vol. 29, no. 3, pp. 215-224, 1989

(Citations:2)

]]>Review of ring perception algorithms for chemical graphshttp://academic.research.microsoft.com/Publication/23984994Sat, 18 May 2013 10:24:47 GMT343682423984994Geoffrey M. Downs, Valerie J. Gillet, John D. Holliday, Michael F. Lynch

J CHEM INF MODEL, vol. 29, no. 3, pp. 172-187, 1989

(Citations:1)

]]>Theoretical aspects of ring perception and development of the extended set of smallest rings concepthttp://academic.research.microsoft.com/Publication/23984995Sat, 18 May 2013 10:24:46 GMT343682423984995Geoffrey M. Downs, Valerie J. Gillet, John D. Holliday, Michael F. Lynch

J CHEM INF MODEL, vol. 29, no. 3, pp. 187-206, 1989

]]>Computer storage and retrieval of generic chemical structures in patents. 9. An algorithm to find the extended set of smallest rings in structurally explicit genericshttp://academic.research.microsoft.com/Publication/23984996Sat, 18 May 2013 10:24:45 GMT343682423984996Geoffrey M. Downs, Valerie J. Gillet, John D. Holliday, Michael F. Lynch

J CHEM INF MODEL, vol. 29, no. 3, pp. 207-214, 1989

]]>Computer storage and retrieval of generic chemical structures in patents. 10. Assignment and logical bubble-up of ring screens for structurally explicit genericshttp://academic.research.microsoft.com/Publication/23984997Sat, 18 May 2013 10:24:44 GMT343682423984997Geoffrey M. Downs, Valerie J. Gillet, John D. Holliday, Michael F. Lynch

J CHEM INF MODEL, vol. 29, no. 3, pp. 215-224, 1989

]]>Automatic classification of chemical structure databases using a highly parallel array processorhttp://academic.research.microsoft.com/Publication/15193732Sat, 18 May 2013 10:24:43 GMT343682415193732Edie M. Rasmussen, Geoffrey M. Downs, Peter Willett

JCC, vol. 9, no. 4, pp. 378-386, 1988

(Citations:4)

]]>Computer storage and retrieval of generic chemical structures in patents. 8. Reduced chemical graphs and their applications in generic chemical structure retrievalhttp://academic.research.microsoft.com/Publication/829719Sat, 18 May 2013 10:24:42 GMT3436824829719Valerie J. Gillet, Geoffrey M. Downs, Ai Ling, Michael F. Lynch, Pallapa Venkataram, Jennifer V. Wood, Winfried Dethlefsen

JCISD, vol. 27, no. 3, pp. 126-137, 1987

(Citations:15)

]]>Computer storage and retrieval of generic chemical structures in patents. 8. Reduced chemical graphs and their applications in generic chemical structure retrievalhttp://academic.research.microsoft.com/Publication/23984900Sat, 18 May 2013 10:24:41 GMT343682423984900Valerie J. Gillet, Geoffrey M. Downs, Ai Ling, Michael F. Lynch, Pallapa Venkataram, Jennifer V. Wood, Winfried Dethlefsen

J CHEM INF MODEL, vol. 27, no. 3, pp. 126-137, 1987

]]>Computer storage and retrieval of generic chemical structures in patents. 7. Parallel simulation of a relaxation algorithm for chemical substructure searchhttp://academic.research.microsoft.com/Publication/830140Sat, 18 May 2013 10:24:40 GMT3436824830140Valerie J. Gillet, Stephen M. Welford, Michael F. Lynch, Peter Willett, John M. Barnard, Geoffrey M. Downs, Gordon A. Manson, J. Thompson

JCISD, vol. 26, no. 3, pp. 118-126, 1986

(Citations:9)

]]>Computer storage and retrieval of generic chemical structures in patents. 7. Parallel simulation of a relaxation algorithm for chemical substructure searchhttp://academic.research.microsoft.com/Publication/23984856Sat, 18 May 2013 10:24:39 GMT343682423984856Valerie J. Gillet, Stephen M. Welford, Michael F. Lynch, Peter Willett, John M. Barnard, Geoff M. Downs, Gordon Manson, J. Thompson

J CHEM INF MODEL, vol. 26, no. 3, pp. 118-126, 1986

(Citations:1)

]]>Clustering Methods and Their Uses in Computational Chemistryhttp://academic.research.microsoft.com/Publication/4478188Sat, 18 May 2013 10:24:38 GMT34368244478188Geoff M. Downs, John M. Barnard

(Citations:31)

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