...with an increasing volume of data. the heterogeneity of data sources
implies heterogeneity in the representation and in the content of data. data may also be incorrect, implicate...analysis of experiments results. our approach aims to ensure the initial quality of data during import into
an information system dedicated to proteomics. it is based on the...
...six bioprocessor plates. we developed a method to detect and discard low quality spectra prior to proteomic profiling data analysis, which uses a correlation matrix to measure the similarities among seldi...correlation matrix was developed as a quality control tool to detect and discard low quality spectra prior to data analysis. it proved to be...
...complexities of field based studies, a statistical technique called meta-analysis can be used. bad or unknown data quality has been largely identified as a major problem in meta-analysis since it generates lack of confidence and inhibits its exploitation. this paper addresses gwas data quality issues and presents a domain specific model for data quality assessment, which has been developed...
Published in 2010.
...mainly in the research laboratory and it is being used to uncover important diagnostic
and prognostic markers that may one...that these methods are
subject to control procedures, in order to ensure that data of the highest quality are obtained. if quality is not controlled,
...of relative intensities for low and high m/z measurements revealed a significant difference of run 21 compared with runs 1, 8, and 17 (p <0.0001...may contribute significant preanalytical bias to proteomic approaches of biomarker discovery. this variation...
Published in 2007.
...3 month intervals. we generated proteomics profiles from
these samples with a stable and reproducible platform for differential proteomics that employs a highly consistent nanofabricated
chipcube™ chromatography...large prospective cohort of healthy and breast cancer patient volunteers and using a nano-fabricated chromatography
system, a consistent lc-ms proteomics dataset has been generated that...
...have been using mass spectroscopy to study cancer. for use of proteomics spectra in a clinical setting, stringent quality-control procedures will be needed. methods...aspirate fluid from healthy breasts and breasts with cancer to prepare a control sample. aliquots of the control sample were used on two...
Published in 2003.
...diagnostic laboratories are increasingly required to meet stringent quality standards, and validated assays are needed to achieve formal accreditation. validation of...exponentially weighted moving average (ewma) control charts with respect to the day to day monitoring of internal quality control samples for the foot and mouth disease solid phase competition...
...will explore the use of a multivariate quality- control chart for application in the clinical laboratory and compare its performance with some traditional clinical monitoring approaches. although the original application of...this sensitivity. recent developments in clinical quality control have focused attention on using quality-control systems de- signed to detect clinically significant changes in the mea...
Published in 1998.